Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL330681 | 1.00 | LMNA (0.59) | LMNACYP2C9KCNH2CYP2D6CYP2C19 | |
| SCHEMBL2181552 | 1.00 | LMNA (0.59) | LMNACYP2C9KCNH2CYP2D6CYP2C19 | |
| SCHEMBL2181688 | 1.00 | LMNA (0.59) | LMNACYP2C9KCNH2CYP2D6CYP2C19 | |
| SCHEMBL31327346 | 1.00 | LMNA (0.59) | LMNACYP2C9KCNH2CYP2D6CYP2C19 | |
| SCHEMBL699895 | 1.00 | LMNA (0.59) | LMNACYP2C9KCNH2CYP2D6CYP2C19 | |
| SCHEMBL8723514 | 1.00 | LMNA (0.59) | LMNACYP2C9KCNH2CYP2D6CYP2C19 | |
| SCHEMBL31327347 | 1.00 | LMNA (0.59) | LMNACYP2C9KCNH2CYP2D6CYP2C19 | |
| Cetrimonium SCHEMBL121980 | 1.00 | LMNA (0.59) | LMNACYP2C9KCNH2CYP2D6CYP2C19 | |
| Cetrimonium SCHEMBL5678134 | 0.98 | KCNH2 (0.57) | LMNACYP2C9KCNH2CYP2D6CYP2C19 | |
| Cetrimonium SCHEMBL28609304 | 0.98 | KCNH2 (0.57) | LMNACYP2C9KCNH2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11929257-B2 | Etching solution and method for aluminum nitride | VERSUM MATERIALS US, LLC (US) | 2024-03-12 | — | — | US | claimed |
| US-20220367199-A1 | ETCHING SOLUTION AND METHOD FOR ALUMINUM NITRIDE | VERSUM MATERIALS US, LLC (US) | 2022-11-17 | — | — | US | claimed |
| EP-3959291-A1 | ETCHING SOLUTION AND METHOD FOR ALUMINUM NITRIDE | Versum Materials US, LLC (US) | 2022-03-02 | — | — | EP | claimed |
| WO-2020185745-A1 | ETCHING SOLUTION AND METHOD FOR ALUMINUM NITRIDE | VERSUM MATERIALS US, LLC (US) | 2020-09-17 | — | — | WO | claimed |
| EP-1812382-B1 | METHOD FOR PRODUCING POLYISOCYANATES | BASF SE (DE) | 2013-01-23 | — | — | EP | claimed |
| US-20090112017-A1 | METHOD FOR PRODUCING POLYISOCYANATES | BASF AKTIENGESSELLSCHAFT (DE) | 2009-04-30 | — | — | US | claimed |
| US-20080305157-A1 | Encapsulation and separation of charged organic solutes inside catanionic vesicles | UNIVERSITY OF MARYLAND OFFICE OF TECHNOLOGY COMMERCIALIZATION (US) | 2008-12-11 | — | — | US | claimed |
| EP-1812382-A1 | METHOD FOR PRODUCING POLYISOCYANATES | BASF AKTIENGESELLSCHAFT (DE) | 2007-08-01 | — | — | EP | claimed |
| WO-2006048171-A1 | METHOD FOR PRODUCING POLYISOCYANATES | BASF AKTIENGESELLSCHAFT (DE) | 2006-05-11 | — | — | WO | claimed |
| US-20250154607-A1 | ISOTHERMAL AMPLIFICATION OF PATHOGENS | BECTON, DICKINSON AND COMPANY | 2025-05-15 | — | — | US | disclosed |
| US-20250059586-A1 | NON-OPAQUE LYTIC BUFFER COMPOSITION FORMULATIONS | BECTON, DICKINSON AND COMPANY | 2025-02-20 | — | — | US | disclosed |
| US-20250059612-A1 | METHOD FOR SEPARATING GENOMIC DNA FOR AMPLIFICATION OF SHORT NUCLEIC ACID TARGETS | BECTON, DICKINSON AND COMPANY | 2025-02-20 | — | — | US | disclosed |
| EP-4473127-A1 | METHOD FOR SEPARATING GENOMIC DNA FOR AMPLIFICATION OF SHORT NUCLEIC ACID TARGETS | Becton, Dickinson and Company (US) | 2024-12-11 | — | — | EP | disclosed |
| EP-4473128-A1 | NON-OPAQUE LYTIC BUFFER COMPOSITION FORMULATIONS | Becton, Dickinson and Company (US) | 2024-12-11 | — | — | EP | disclosed |
| WO-2009013062-A1 | PROCESS FOR THE SYNTHESIS OF CARBAMATES USING CO2 | HUNTSMAN INTERNATIONAL LLC (US) | 2009-01-29 | — | — | WO | disclosed |
| EP-2011782-A1 | Process for the synthesis of carbamates using co2 | HUNTSMAN INTERNATIONAL LLC (US) | 2009-01-07 | — | — | EP | disclosed |
| US-20080305157-A1 | Encapsulation and separation of charged organic solutes inside catanionic vesicles | UNIVERSITY OF MARYLAND OFFICE OF TECHNOLOGY COMMERCIALIZATION (US) | 2008-12-11 | — | — | US | disclosed |
| EP-1812382-A1 | METHOD FOR PRODUCING POLYISOCYANATES | BASF AKTIENGESELLSCHAFT (DE) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006048171-A1 | METHOD FOR PRODUCING POLYISOCYANATES | BASF AKTIENGESELLSCHAFT (DE) | 2006-05-11 | — | — | WO | disclosed |
| US-5165994-A | Spontaneous equilbrium surfactant vesicles | UNIVERSITY OF DELAWARE (US) | 1992-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090112017-A1 | METHOD FOR PRODUCING POLYISOCYANATES | PGLS, INMT, PNMT | LMNA 1276/4885CYP2C9 565/4885KCNH2 862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.