Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.53 |
| ▸ | NOS2 | P35228 | 4/20 | 0.37 |
| ▸ | NOS3 | P29474 | 3/20 | 0.37 |
| ▸ | NOS1 | P29475 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | BHMT | Q93088 | 3/20 | 0.36 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.36 |
| ▸ | ARG2 | P78540 | 4/20 | 0.36 |
| ▸ | ARG1 | P05089 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL28275584 | 0.90 | GSR (0.65) | GSRNOS2NOS3NOS1CYP2C19 | |
| Lysine SCHEMBL3312731 | 0.89 | GSR (0.62) | GSRNOS2NOS3NOS1CYP2C19 | |
| Lysine SCHEMBL3312740 | 0.89 | GSR (0.62) | GSRNOS2NOS3NOS1CYP2C19 | |
| Methionine SCHEMBL353438 | 0.89 | BHMT (0.44) | GSRNOS2NOS3NOS1CYP2C19 | |
| Racemethionine SCHEMBL353437 | 0.89 | BHMT (0.44) | GSRNOS2NOS3NOS1CYP2C19 | |
| Lysine SCHEMBL7113285 | 0.89 | GSR (0.67) | GSRNOS2NOS3NOS1CYP2C19 | |
| Lysine SCHEMBL20530995 | 0.89 | GSR (0.67) | GSRNOS2NOS3NOS1CYP2C19 | |
| Lysine SCHEMBL7113294 | 0.89 | GSR (0.67) | GSRNOS2NOS3NOS1CYP2C19 | |
| Lysine SCHEMBL1345092 | 0.86 | GSR (0.71) | GSRNOS2NOS3NOS1CYP2C19 | |
| Lysine SCHEMBL8720001 | 0.86 | GSR (0.71) | GSRNOS2NOS3NOS1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106107034-A | A kind of piglets feedstuff replacing milk | 郑州诺尔畜牧饲料有限公司 | 2016-11-16 | — | — | CN | disclosed |