Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.41 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 13/20 | 0.36 |
| ▸ | FAP | Q12884 | 2/20 | 0.36 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6005743 | 0.92 | ALDH1A1 (0.48) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| Hydrochloric Acid SCHEMBL3726196 | 0.74 | ALDH1A1 (0.40) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL9866155 | 0.73 | KDM4E (0.36) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL8324882 | 0.71 | CHRM2 (0.42) | CHRM2DPP4 | |
| SCHEMBL9865852 | 0.70 | CHRM1 (0.34) | CHRM1 | |
| SCHEMBL9129070 | 0.70 | PIM1 (0.37) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL10730540 | 0.70 | KCNH2 (0.52) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9129061 | 0.70 | PIM1 (0.37) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL10700723 | 0.69 | ALDH1A1 (0.66) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL6588035 | 0.69 | PIM1 (0.38) | ALDH1A1POLBCHRM2CHRM1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8415342-B2 | Besifloxacin ophthalmic composition for the treatment or control of infection | BAUSCH & LOMB INCORPORATED (US) | 2013-04-09 | — | — | US | disclosed |
| WO-2010051291-A1 | BESIFLOXACIN OPHTHALMIC COMPOSITION FOR THE TREATMENT OR CONTROL OF INFECTION | BAUSCH & LOMB INCORPORATED (US) | 2010-05-06 | — | — | WO | disclosed |
| US-20100105662-A1 | Besifloxacin Ophthalmic Composition for the Treatment or Control of Infection | MEDICIS PHARMACEUTICAL CORPORATION | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105662-A1 | Besifloxacin Ophthalmic Composition for the Treatment or Control of Infection | BLM, BROX, CRYAB | ALDH1A1 4717/4885POLB 141/4885CHRM2 4370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.