Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29514514 | 0.91 | CYP2C9 (0.59) | TSHRCYP2C9CYP3A4HIF1ACYP2D6 | |
| SCHEMBL3319867 | 0.80 | CYP2C9 (0.54) | TSHRCYP2C9CYP3A4HIF1ACYP2D6 | |
| Trifluoroacetic Acid SCHEMBL6986818 | 0.79 | CHKA (0.63) | TSHRCYP2C9CYP3A4HIF1ACYP2D6 | |
| Trifluoroacetic Acid SCHEMBL1456945 | 0.74 | DPP4 (0.59) | TSHRCYP2C9CYP3A4HIF1ACYP2D6 | |
| Trifluoroacetic Acid SCHEMBL1648792 | 0.74 | ITGB3 (0.56) | SLC2A1CYP2C19ITGB3ITGA2B | |
| SCHEMBL15850038 | 0.74 | AKR1C3 (0.47) | CYP2C9CYP3A4CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL949324 | 0.74 | MAPT (0.47) | CYP2C9CYP1A2CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL3315322 | 0.72 | CYP2C9 (0.51) | TSHRCYP2C9CYP3A4HIF1ACYP2D6 | |
| SCHEMBL7398141 | 0.72 | ITGB3 (0.50) | TSHRCYP2C9CYP3A4HIF1ACYP2D6 | |
| SCHEMBL641121 | 0.72 | CYP2C9 (0.75) | TSHRCYP2C9CYP3A4HIF1ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8227506-B2 | Benzamidine compound | AJINOMOTO., INC. (JP) | 2012-07-24 | — | — | US | disclosed |
| US-20100105731-A2 | NOVEL BENZAMIDINE COMPOUND | AJINOMOTO CO., INC. (JP) | 2010-04-29 | — | — | US | disclosed |
| US-20080021065-A1 | NOVEL BENZAMIDINE COMPOUND | AJINOMOTO CO. INC (JP) | 2008-01-24 | — | — | US | disclosed |
| EP-1847527-A1 | NOVEL BENZAMIDINE COMPOUND | Ajinomoto Co., Inc. (JP) | 2007-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105731-A2 | NOVEL BENZAMIDINE COMPOUND | SERPINC1, F11, TFPI | TSHR 1617/4885CYP2C9 460/4885CYP3A4 1674/4885 |
| US-20080021065-A1 | NOVEL BENZAMIDINE COMPOUND | SERPINC1, F11, TFPI | TSHR 1617/4885CYP2C9 460/4885CYP3A4 1674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.