Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 8/20 | 0.54 |
| ▸ | TSHR | P16473 | 7/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3319861 | 0.80 | TSHR (0.55) | CYP2C9TSHRHIF1ACYP2D6CYP3A4 | |
| SCHEMBL3315322 | 0.77 | CYP2C9 (0.51) | CYP2C9TSHRHIF1ACYP2D6CYP3A4 | |
| SCHEMBL29514514 | 0.76 | CYP2C9 (0.59) | CYP2C9TSHRHIF1ACYP2D6CYP3A4 | |
| SCHEMBL1025273 | 0.71 | ITGB3 (0.45) | CYP2C9TSHRHIF1ACYP2D6CYP3A4 | |
| SCHEMBL3096735 | 0.71 | CYP2C9 (1.00) | CYP2C9TSHRHIF1ACYP2D6CYP3A4 | |
| SCHEMBL3095008 | 0.69 | CYP2C9 (0.83) | CYP2C9TSHRHIF1ACYP2D6CYP3A4 | |
| SCHEMBL6187083 | 0.69 | HIF1A (0.60) | CYP2C9TSHRHIF1ACYP2D6CYP3A4 | |
| SCHEMBL23875490 | 0.69 | CHKA (0.59) | CYP2C9TSHRHIF1ACYP2D6CYP3A4 | |
| SCHEMBL484823 | 0.68 | HIF1A (0.74) | CYP2C9TSHRHIF1ACYP2D6CYP3A4 | |
| SCHEMBL13168270 | 0.68 | CYP2C9 (0.62) | CYP2C9TSHRHIF1ACYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8227506-B2 | Benzamidine compound | AJINOMOTO., INC. (JP) | 2012-07-24 | — | — | US | disclosed |
| US-20100105731-A2 | NOVEL BENZAMIDINE COMPOUND | AJINOMOTO CO., INC. (JP) | 2010-04-29 | — | — | US | disclosed |
| US-20080021065-A1 | NOVEL BENZAMIDINE COMPOUND | AJINOMOTO CO. INC (JP) | 2008-01-24 | — | — | US | disclosed |
| EP-1847527-A1 | NOVEL BENZAMIDINE COMPOUND | Ajinomoto Co., Inc. (JP) | 2007-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105731-A2 | NOVEL BENZAMIDINE COMPOUND | SERPINC1, F11, TFPI | CYP2C9 460/4885TSHR 1617/4885HIF1A 4623/4885 |
| US-20080021065-A1 | NOVEL BENZAMIDINE COMPOUND | SERPINC1, F11, TFPI | CYP2C9 460/4885TSHR 1617/4885HIF1A 4623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.