Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.78 |
| ▸ | CYP11B1 | P15538 | 9/20 | 0.70 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.67 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.64 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.64 |
| ▸ | FNTA | P49354 | 1/20 | 0.62 |
| ▸ | FNTB | P49356 | 1/20 | 0.62 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.62 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | QPCT | Q16769 | 1/20 | 0.61 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.61 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11702884 | 0.91 | CYP19A1 (0.67) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL6057478 | 0.86 | CYP11B1 (0.68) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL1024261 | 0.85 | CYP11B1 (0.84) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL11706257 | 0.83 | KDM4E (0.68) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL2728811 | 0.83 | CYP11B1 (1.00) | CYP19A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL1775141 | 0.83 | CYP11B1 (0.81) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL22746812 | 0.83 | CYP11B1 (0.67) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL20601860 | 0.81 | TBXAS1 (0.67) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL10508142 | 0.81 | MEN1 (0.69) | CYP19A1TBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30023445 | 0.81 | TBXAS1 (0.66) | CYP19A1CYP11B1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117098761-A | Imidazo [4,5-d ] pyridazine derivatives, preparation thereof and therapeutic use thereof | 赛诺菲 | 2023-11-21 | — | — | CN | disclosed |
| WO-2022050774-A1 | NOVEL IMIDAZOLE DERIVATIVE SALT HAVING ANTIFUNGAL ACTIVITY, AND USE THEREOF | 경희대학교 산학협력단 | 2022-03-10 | — | — | WO | disclosed |
| WO-2018143314-A1 | POLYIMIDE PRECURSOR COMPOSITION | 東京応化工業株式会社 | 2018-08-09 | — | — | WO | disclosed |
| US-10023540-B2 | Hydrogen barrier agent, hydrogen barrier film forming composition, hydrogen barrier film, method for producing hydrogen barrier film, and electronic element | TOKYO OHKA KOGYO CO., LTD. (JP) | 2018-07-17 | — | — | US | disclosed |
| US-10023540-B2 | Hydrogen barrier agent, hydrogen barrier film forming composition, hydrogen barrier film, method for producing hydrogen barrier film, and electronic element | TOKYO OHKA KOGYO CO., LTD. (JP) | 2018-07-17 | — | — | US | disclosed |
| US-9981914-B2 | — | — | 2018-05-29 | — | — | US | disclosed |
| US-9981914-B2 | — | — | 2018-05-29 | — | — | US | disclosed |
| US-20180086717-A1 | HYDROGEN BARRIER AGENT, HYDROGEN BARRIER FILM FORMING COMPOSITION, HYDROGEN BARRIER FILM, METHOD FOR PRODUCING HYDROGEN BARRIER FILM, AND ELECTRONIC ELEMENT | TOKYO OHKA KOGYO CO., LTD. (JP) | 2018-03-29 | — | — | US | disclosed |
| US-20180086717-A1 | HYDROGEN BARRIER AGENT, HYDROGEN BARRIER FILM FORMING COMPOSITION, HYDROGEN BARRIER FILM, METHOD FOR PRODUCING HYDROGEN BARRIER FILM, AND ELECTRONIC ELEMENT | TOKYO OHKA KOGYO CO., LTD. (JP) | 2018-03-29 | — | — | US | disclosed |
| CN-104447557-B | A kind of preparation method of N arylpyrazoles compound and N aryl imidazoles | 苏州大学 | 2017-08-25 | — | — | CN | disclosed |
| EP-0656359-A1 | Substituted 6,11-ethano-6,11-dihydrobenzo[b]quinolizinium salts and compositionsand methods of use thereof | STERLING WINTHROP INC. (US) | 1995-06-07 | — | — | EP | disclosed |
| EP-0647641-A1 | Substituted heterocyclylisoquinolinium salts and compositions and methods of usethereof | STERLING WINTHROP INC. (US) | 1995-04-12 | — | — | EP | disclosed |
| US-4863944-A | Dopamine-β-hydroxylase inhibitors | SMITHKLINE BECKMAN CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0125783-B1 | DOPAMINE-BETA-HYDROXYLASE INHIBITORS | SMITHKLINE BECKMAN CORPORATION (US) | 1989-01-04 | — | — | EP | disclosed |
| US-4772723-A | Dopamine β-hydroxylase inhibitors | SMITHKLINE BECKMAN CORPORATION (US) | 1988-09-20 | — | — | US | disclosed |
| US-4743613-A | Ester prodrugs of dopamine-β-hydroxylase, inhibitors, composition containing them, and method of using them to inhibit dopamine-β-hydroxylase activity | SMITHKLINE BECKMAN CORPORATION (US) | 1988-05-10 | — | — | US | disclosed |
| EP-0244956-A1 | Ester prodrugs of dopamine-beta-hydroxylase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1987-11-11 | — | — | EP | disclosed |
| US-4632934-A | THROMBOXANE SYNTHETASE INHIBITORS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1986-12-30 | — | — | US | disclosed |
| US-4532331-A | 1-Benzyl-2-aminomethyl imidazole derivatives | SMITHKLINE BECKMAN CORPORATION (US) | 1985-07-30 | — | — | US | disclosed |
| EP-0125783-A1 | Dopamine-beta-hydroxylase inhibitors | SMITHKLINE BECKMAN CORPORATION (US) | 1984-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086717-A1 | HYDROGEN BARRIER AGENT, HYDROGEN BARRIER FILM FORMING COMPOSITION, HYDROGEN BARRIER FILM, METHOD FOR PRODUCING HYDROGEN BARRIER FILM, AND ELECTRONIC ELEMENT | SLC9A2, SLC9A1, NHERF1 | CYP19A1 820/4885CYP11B1 2697/4885CYP11B2 1971/4885 |
| US-10023540-B2 | Hydrogen barrier agent, hydrogen barrier film forming composition, hydrogen barrier film, method for producing hydrogen barrier film, and electronic element | SLC9A2, SLC9A1, NHERF1 | CYP19A1 820/4885CYP11B1 2697/4885CYP11B2 1971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.