Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | BPTF | Q12830 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3456257 | 0.81 | ALDH1A1 (0.76) | ALDH1A1ALOX12BPTFDPP4HSD11B1 | |
| SCHEMBL3323811 | 0.81 | HSD11B1 (0.65) | ALDH1A1HSD11B1TSHRGRM1SLC6A2 | |
| SCHEMBL6973736 | 0.76 | ALDH1A1 (0.56) | ALDH1A1ALOX12BPTFDPP4HSD11B1 | |
| SCHEMBL22481607 | 0.76 | HSP90AA1 (0.47) | ALDH1A1TSHRSLC6A2SLC6A4HSP90AA1 | |
| SCHEMBL19296215 | 0.76 | HSP90AA1 (0.50) | ALDH1A1TSHRSLC6A2SLC6A4HSP90AA1 | |
| SCHEMBL2962273 | 0.73 | HSP90AA1 (0.50) | ALDH1A1TSHRSLC6A2SLC6A4HSP90AA1 | |
| SCHEMBL3322456 | 0.73 | ALDH1A1 (0.58) | ALDH1A1ALOX12LMNAMAPTMAPK1 | |
| SCHEMBL640879 | 0.72 | BPTF (0.70) | ALDH1A1ALOX12BPTFDPP4HSD11B1 | |
| SCHEMBL2023735 | 0.72 | HSP90AA1 (0.51) | ALDH1A1TSHRSLC6A2SLC6A4HSP90AA1 | |
| SCHEMBL4253684 | 0.70 | HSP90AA1 (0.50) | ALDH1A1TSHRSLC6A2SLC6A4HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120789-A1 | Compound | STERIX LIMITED (GB) | 2010-05-13 | — | — | US | disclosed |
| US-20100120789-A1 | Compound | STERIX LIMITED (GB) | 2010-05-13 | — | — | US | disclosed |
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | STERIX LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | STERIX LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | HSD3B1, HSD3B2, HSD11B1 | ALDH1A1 437/4885ALOX12 1459/4885BPTF 3966/4885 |
| US-20100120789-A1 | Compound | NR0B2, NR0B1, NR4A1 | ALDH1A1 3143/4885ALOX12 2739/4885BPTF 3011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.