Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | DRD1 | P21728 | 3/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12810928 | 0.90 | AKR1C3 (0.45) | HSP90AA1AKR1C3PRMT5WDR77SLC6A4 | |
| SCHEMBL5425390 | 0.88 | PNMT (0.58) | HSP90AA1AKR1C3PRMT5WDR77SLC6A4 | |
| SCHEMBL28890035 | 0.87 | HSP90AA1 (0.46) | HSP90AA1AKR1C3PRMT5WDR77SLC6A4 | |
| SCHEMBL21899394 | 0.86 | HSP90AA1 (0.55) | HSP90AA1AKR1C3PRMT5WDR77DRD1 | |
| SCHEMBL4253684 | 0.84 | HSP90AA1 (0.50) | HSP90AA1AKR1C3PRMT5WDR77SLC6A4 | |
| SCHEMBL8680487 | 0.84 | NOTUM (0.57) | HSP90AA1AKR1C3PRMT5WDR77SLC6A4 | |
| SCHEMBL2962273 | 0.84 | HSP90AA1 (0.50) | HSP90AA1AKR1C3PRMT5WDR77SLC6A4 | |
| SCHEMBL19722818 | 0.84 | HSP90AA1 (0.50) | HSP90AA1AKR1C3PRMT5WDR77SLC6A4 | |
| SCHEMBL31486299 | 0.83 | HSP90AA1 (0.41) | HSP90AA1AKR1C3PRMT5WDR77SLC6A4 | |
| SCHEMBL3992345 | 0.82 | HSP90AA1 (0.52) | HSP90AA1AKR1C3PRMT5WDR77ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4596555-A1 | ABHD6 ANTAGONIST | ONO Pharmaceutical Co., Ltd. (JP) | 2025-08-06 | — | — | EP | claimed |
| WO-2024071398-A1 | ABHD6 ANTAGONIST | 小野薬品工業株式会社 | 2024-04-04 | — | — | WO | claimed |
| US-20260083735-A1 | ABHD6 ANTAGONIST | ONO PHARMACEUTICAL CO., LTD. (JP) | 2026-03-26 | — | — | US | disclosed |
| EP-4596555-A1 | ABHD6 ANTAGONIST | ONO Pharmaceutical Co., Ltd. (JP) | 2025-08-06 | — | — | EP | disclosed |
| WO-2024071398-A1 | ABHD6 ANTAGONIST | 小野薬品工業株式会社 | 2024-04-04 | — | — | WO | disclosed |
| CN-112159401-A | Biased agonist and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2021-01-01 | — | — | CN | disclosed |
| CN-107922430-B | 2-substituted benzimidazole-4-formamide compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2020-09-04 | — | — | CN | disclosed |
| WO-2020132378-A2 | COMPOSITIONS AND METHODS OF TREATMENT FOR NEUROLOGICAL DISORDERS COMPRISING DEPRESSION | GLIAPHARM SA (CH) | 2020-06-25 | — | — | WO | disclosed |
| EP-1831207-B1 | AMINOPYRIMIDINE COMPOUNDS AS PLK INHIBITORS | AMGEN INC (US) | 2012-11-14 | — | — | EP | disclosed |
| US-7968719-B2 | Indazole derivatives as inhibitors of hormone sensitive lipase | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2011-06-28 | — | — | US | disclosed |
| US-7858785-B2 | Aminopyrimidine compounds and methods of use | AMGEN INC. (US) | 2010-12-28 | — | — | US | disclosed |
| US-20100010014-A1 | AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2010-01-14 | — | — | US | disclosed |
| US-20090215824-A1 | INDAZOLE DERIVATIVES AS INHIBITORS OF HORMONE SENSITIVE LIPASE | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-08-27 | — | — | US | disclosed |
| US-7528155-B2 | Indazole derivatives as inhibitors of hormone sensitive lipase | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-05-05 | — | — | US | disclosed |
| WO-2009049028-A1 | PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USE AS JANUS KINASE MODULATORS | TARGEGEN INC. (US) | 2009-04-16 | — | — | WO | disclosed |
| CN-101068804-A | Bissulfonamide compounds as agonists of GalR1, compositions, and methods of use | TRANSTECH PHARMA INC (US) | 2007-11-07 | — | — | CN | disclosed |
| EP-1831207-A1 | AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE | Amgen Inc. (US) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006066172-A1 | AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE | AMGEN, INC. (US) | 2006-06-22 | — | — | WO | disclosed |
| US-20050197348-A1 | Indazole derivatives as inhibitors of hormone sensitive lipase | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-09-08 | — | — | US | disclosed |
| US-4147787-A | ANTICOAGULANTS | PARCOR (FR) | 1979-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100010014-A1 | AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE | PLK1, TYMP, TK2 | HSP90AA1 2038/4885AKR1C3 2685/4885PRMT5 671/4885 |
| US-20090215824-A1 | INDAZOLE DERIVATIVES AS INHIBITORS OF HORMONE SENSITIVE LIPASE | LIPE, PNLIP, CEL | HSP90AA1 744/4885AKR1C3 1505/4885PRMT5 1683/4885 |
| US-20050197348-A1 | Indazole derivatives as inhibitors of hormone sensitive lipase | LIPE, PNLIP, CEL | HSP90AA1 744/4885AKR1C3 1505/4885PRMT5 1683/4885 |
| US-20260083735-A1 | ABHD6 ANTAGONIST | ABHD6, ABHD16A, ABHD12 | HSP90AA1 916/4885AKR1C3 1262/4885PRMT5 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.