Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5318777 | 0.86 | HPGD (0.44) | CYP2D6CYP2C19PAOXMMEACE | |
| SCHEMBL3322029 | 0.81 | CA3 (0.35) | TSHRPAOXMMEACECPA1 | |
| SCHEMBL28765547 | 0.79 | ALDH1A1 (0.52) | CYP2D6MMEACECPA1ACE2 | |
| SCHEMBL5458833 | 0.77 | FNTA (0.46) | MMEACECPA1ACE2FNTA | |
| SCHEMBL3297498 | 0.75 | ALDH1A1 (0.50) | MMEACECPA1ACE2FNTA | |
| SCHEMBL3291470 | 0.75 | ALDH1A1 (0.48) | TSHRMMEACECPA1ACE2 | |
| SCHEMBL5471965 | 0.73 | TDP1 (0.46) | TSHRMMEACECPA1ACE2 | |
| SCHEMBL4654662 | 0.71 | ALDH1A1 (0.50) | TSHRHSD17B10MEN1ALDH1A1ALOX15 | |
| SCHEMBL5463763 | 0.70 | DNM1 (0.42) | PAOXHPGDHSD17B10TDP1ABCB11 | |
| SCHEMBL5468515 | 0.69 | TDP1 (0.50) | TSHRMMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7731936-B2 | Metal complexes based on tetrathiol ligands and their use in nuclear medical diagnostics and endoradionuclide therapy and method for producing said metal complexes | FORSCHUNGSZENTRUM ROSSENDORF E,V (DE) | 2010-06-08 | — | — | US | disclosed |
| US-20080279770-A1 | Metal Complexes Based on Tetrathiol Ligands and Their Use in Nuclear Medical Diagnostics and Endoradionuclide Therapy and Method For Producing Said Metal Complexes | FORSCHUNGSZENTRUM ROSSENDORF E.V. (DE) | 2008-11-13 | — | — | US | disclosed |
| EP-1742898-A1 | METAL COMPLEXES BASED ON TETRATHIOL LIGANDS AND THEIR USE IN NUCLEAR MEDICAL DIAGNOSTICS AND ENDORADIONUCLIDE THERAPY AND METHOD FOR PRODUCING SAID METAL COMPLEXES | Forschungszentrum Rossendorf e.V. (DE) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005108330-A1 | METAL COMPLEXES BASED ON TETRATHIOL LIGANDS AND THEIR USE IN NUCLEAR MEDICAL DIAGNOSTICS AND ENDORADIONUCLIDE THERAPY AND METHOD FOR PRODUCING SAID METAL COMPLEXES | FORSCHUNGSZENTRUM ROSSENDORF E.V. (DE) | 2005-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080279770-A1 | Metal Complexes Based on Tetrathiol Ligands and Their Use in Nuclear Medical Diagnostics and Endoradionuclide Therapy and Method For Producing Said Metal Complexes | NTSR1, TSHR, NGLY1 | TSHR 2/4885CYP3A4 4204/4885CYP2D6 4013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.