SCHEMBL332246

SCHEMBL332246

O=S(=O)(O)[CH]c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
ALDH1A1 P00352 4/20 0.43
CYP2A6 P11509 1/20 0.43
CYP2D6 P10635 2/20 0.41
MAPT P10636 2/20 0.41
CYP1A2 P05177 2/20 0.41
LMNA P02545 2/20 0.41
HDAC3 O15379 1/20 0.41
TNKS O95271 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HCAR2 Q8TDS4 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
TNKS2 Q9H2K2 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Z)-1,2-Diphenylethene SCHEMBL8520704 0.76 LMNA (0.54) SMN1; SMN2ALDH1A1CYP2D6MAPTCYP1A2
(Z)-1,2-Diphenylethene SCHEMBL8520705 0.76 LMNA (0.54) SMN1; SMN2ALDH1A1CYP2D6MAPTCYP1A2
SCHEMBL15001 0.75 PPARG (0.53) SMN1; SMN2ALDH1A1CYP2D6MAPTCYP1A2
SCHEMBL27295260 0.75 HSD11B1 (0.45) NFE2L2
SCHEMBL27293332 0.75 JUN (0.45) SMN1; SMN2MAPTCYP1A2HDAC1HDAC6
SCHEMBL1201904 0.75 PPARG (0.53) SMN1; SMN2ALDH1A1CYP2D6MAPTCYP1A2
SCHEMBL27542774 0.75 CYP2A6 (0.48) SMN1; SMN2CYP2A6MAPTCYP1A2LMNA
SCHEMBL27279220 0.75 HSD17B10 (0.48) ALDH1A1CYP2A6CYP1A2LMNAMAOB
SCHEMBL2496181 0.75 PPARG (0.53) SMN1; SMN2ALDH1A1CYP2D6MAPTCYP1A2
SCHEMBL525688 0.74 ALDH1A1 (0.43) TSHRSMN1; SMN2ALDH1A1CYP2A6CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 687 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114040779-A Conjugates of cell binding molecules containing branched linkers and cytotoxic agents 杭州多禧生物科技有限公司 2022-02-11 CN claimed
US-8536329-B2 Reactive dye EVERLIGHT USA, INC. (US) 2013-09-17 US claimed
CN-103288815-A Beta-lactamyl vasopression V1a antagonists AZEVAN PHARMACEUTICALS INC 2013-09-11 CN claimed
EP-1874463-B1 NANOCATALYST ANCHORED ONTO ACID FUNCTIONALIZED SOLID SUPPORT AND METHODS OF MAKING AND USING SAME HEADWATERS TECH INNOVATION LLC (US) 2013-05-29 EP claimed
US-20120264922-A1 REACTIVE DYE EVERLIGHT USA, INC. (US) 2012-10-18 US claimed
EP-2511347-A1 Reactive dye Everlight USA, Inc. (US) 2012-10-17 EP claimed
CN-102711789-A Therapeutic agents for reducing parathyroid hormone levels KAI PHARMACEUTICALS INC 2012-10-03 CN claimed
CN-101921267-A Beta-lactam Hou Yejiayasu V 1aAntagonist AZEVAN PHARMACEUTICALS INC 2010-12-22 CN claimed
CN-101589056-A Depsipeptide and therepic use thereof UNIV SOUTHAMPTON (GB) 2009-11-25 CN claimed
WO-2007084904-A2 METHODS FOR MANUFACTURING FUNCTIONALIZED INORGANIC OXIDES AND POLYMERS INCORPORATING SAME HEADWATERS TECHNOLOGY INNOVATION LLC (US) 2007-07-26 WO claimed
EP-0012283-B1 PROCESS FOR PREPARING BASIC DYESTUFFS BAYER AG (DE) 1981-09-23 EP claimed
US-4260776-A PYRAZOLONE BAYER AKTIENGESELLSCHAFT (DE) 1981-04-07 US claimed
EP-0022520-A1 Preparation of basic triaryl methane dyestuffs BAYER AG (DE) 1981-01-21 EP claimed
EP-0014031-A1 Water-soluble monoazo dyes of the azobenzene series, their preparation and process for the colouration of polyamide textile materials IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-08-06 EP claimed
EP-0012283-A1 Process for preparing basic dyestuffs BAYER AG (DE) 1980-06-25 EP claimed
US-4185013-A Anionic azo dyes having a 3-dibenzofuranyl diazo component radical optionally having a 2- or 8-sulfo group SANDOZ LTD. (CH) 1980-01-22 US claimed
US-4145341-A WATER-SOLUBLE AZO DYES CONTAINING DIAMINOPYRIMIDINE COUPLER COMPONENTS BASF AKTIENGESELLSCHAFT (DE) 1979-03-20 US claimed
US-4124581-A FOR NATURAL AND SYNTHETIC FIBERS, COLORFAST BAYER AKTIENGESELLSCHAFT (DE) 1978-11-07 US claimed
US-4051134-A Reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-09-27 US claimed
US-4039530-A INTERMEDIATES FOR CEPHALOSPORINS AND PENICILLINS CONNLAB HOLDINGS LIMITED (CA) 1977-08-02 US claimed