Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2160443 | 0.68 | — | — | |
| SCHEMBL710691 | 0.67 | — | — | |
| SCHEMBL4933561 | 0.66 | EPHX2 (0.32) | CES2CES1 | |
| SCHEMBL3435591 | 0.66 | ALOX5 (0.43) | ALOX5CES2CES1KEAP1 | |
| SCHEMBL3323311 | 0.64 | ALOX5 (0.39) | ALOX5CES2CES1KEAP1 | |
| SCHEMBL6854795 | 0.62 | — | — | |
| SCHEMBL9814779 | 0.61 | ALOX5 (0.50) | ALOX5CES2CES1KEAP1 | |
| SCHEMBL6744675 | 0.61 | — | — | |
| SCHEMBL6651045 | 0.60 | ALOX5 (0.46) | ALOX5EPHX1CES2CES1KEAP1 | |
| SCHEMBL7130933 | 0.60 | SLC6A4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120789-A1 | Compound | STERIX LIMITED (GB) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120789-A1 | Compound | NR0B2, NR0B1, NR4A1 | ALOX5 2461/4885EPHX1 2880/4885CES2 1306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.