Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3435591 | 0.82 | ALOX5 (0.43) | ALOX5CES2CES1KEAP1MAPT | |
| SCHEMBL6828713 | 0.76 | CES2 (0.42) | ALOX5CES2CES1KEAP1MAPT | |
| SCHEMBL515707 | 0.72 | ALOX5 (0.42) | ALOX5SLC6A3CES2CES1KEAP1 | |
| SCHEMBL9814779 | 0.68 | ALOX5 (0.50) | ALOX5CES2CES1KEAP1HPGD | |
| SCHEMBL10408648 | 0.67 | AKR1C1 (0.43) | GAAAKR1C1 | |
| SCHEMBL1568577 | 0.66 | HPGD (0.44) | ALOX5MAPTHPGDALDH1A1 | |
| SCHEMBL13163250 | 0.66 | ALOX5 (0.51) | ALOX5CES2CES1KEAP1MAPT | |
| SCHEMBL7955355 | 0.66 | CES2 (0.61) | ALOX5CES2CES1KEAP1MAPT | |
| SCHEMBL5027606 | 0.66 | ALOX5 (0.51) | ALOX5CES2CES1KEAP1MAPT | |
| SCHEMBL8853390 | 0.64 | ALOX5 (0.50) | ALOX5CES2CES1KEAP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120789-A1 | Compound | STERIX LIMITED (GB) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120789-A1 | Compound | NR0B2, NR0B1, NR4A1 | ALOX5 2461/4885SLC6A3 2244/4885CES2 1306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.