SCHEMBL3323740

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7705995	0.81	P2RX7 (0.71)	P2RX7MEN1KMT2AEPHX2HPGD
	SCHEMBL13333015	0.76	CYP17A1 (1.00)	P2RX7MEN1KMT2ACYP17A1CYP19A1
	SCHEMBL1947902	0.76	SMN1; SMN2 (0.66)	P2RX7MEN1KMT2AALDH1A1TP53
	SCHEMBL13333016	0.74	HSD11B1 (0.77)	P2RX7MEN1KMT2ACYP17A1CYP19A1
	SCHEMBL3324030	0.74	CYP17A1 (0.72)	P2RX7USP2EPHX2CYP17A1CYP19A1
	SCHEMBL31552469	0.74	P2RX7 (0.60)	P2RX7MEN1KMT2AEPHX2TP53
	SCHEMBL25408547	0.74	HTT (0.59)	MEN1USP2KMT2AEPHX2ALDH1A1
	SCHEMBL31435464	0.74	HTT (0.59)	MEN1USP2KMT2AEPHX2ALDH1A1
	SCHEMBL1073464	0.73	SMN1; SMN2 (0.65)	P2RX7MEN1KMT2AEPHX2HSD11B1
	SCHEMBL11741818	0.73	P2RX7 (0.75)	P2RX7MEN1KMT2AEPHX2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.