Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.60 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.52 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3324037 | 1.00 | PLA2G1B (0.60) | PLA2G1BATG4BMEN1KMT2ACYP3A4 | |
| SCHEMBL7720432 | 0.88 | GPR119 (0.52) | PLA2G1BATG4BMEN1KMT2ACYP3A4 | |
| SCHEMBL406827 | 0.86 | GPR119 (0.62) | GPR119USP30HPGDPKM | |
| SCHEMBL17820564 | 0.83 | KMT2A (0.48) | PLA2G1BATG4BMEN1KMT2AUSP30 | |
| SCHEMBL969043 | 0.82 | ALDH1A1 (0.58) | PLA2G1BATG4BMEN1KMT2AGPR119 | |
| SCHEMBL3325048 | 0.82 | ALDH1A1 (0.58) | PLA2G1BATG4BMEN1KMT2AGPR119 | |
| SCHEMBL969044 | 0.82 | ALDH1A1 (0.58) | PLA2G1BATG4BMEN1KMT2AGPR119 | |
| SCHEMBL28195229 | 0.82 | PKM (0.51) | PLA2G1BATG4BMEN1KMT2AGPR119 | |
| SCHEMBL22449355 | 0.81 | USP30 (0.69) | GPR119USP30GRM5 | |
| SCHEMBL31451464 | 0.81 | USP30 (0.69) | GPR119USP30GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120858-A1 | Piperidine Derivatives | PFIZER INC. | 2010-05-13 | — | — | US | disclosed |
| EP-2066630-A1 | PIPERIDINE DERIVATIVES | Pfizer Products Incorporated (US) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008023258-A1 | PIPERIDINE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2008-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120858-A1 | Piperidine Derivatives | P2RX5, P2RX7, P2RX1 | PLA2G1B 402/4885ATG4B 2886/4885MEN1 2104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.