Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3800899 | 0.82 | PDE10A (0.47) | ALDH1A1POLBMAPTHSD17B10KDM4E | |
| SCHEMBL718474 | 0.82 | HSP90AA1 (0.54) | ALDH1A1MAPTHSD17B10KDM4EBLM | |
| SCHEMBL23162725 | 0.78 | MAPT (0.42) | ALDH1A1POLBMAPTHSD17B10KDM4E | |
| SCHEMBL23204380 | 0.78 | DYRK1A (0.45) | ALDH1A1POLBMAPTHSD17B10KDM4E | |
| SCHEMBL17336762 | 0.78 | KDM4E (0.60) | ALDH1A1POLBMAPTHSD17B10KDM4E | |
| SCHEMBL5016163 | 0.77 | SMN1; SMN2 (0.54) | ALDH1A1POLBMAPTHSD17B10KDM4E | |
| SCHEMBL5016286 | 0.76 | KDM4E (0.66) | ALDH1A1POLBMAPTHSD17B10KDM4E | |
| SCHEMBL1671400 | 0.76 | ALDH1A1 (0.57) | ALDH1A1POLBMAPTHSD17B10KDM4E | |
| SCHEMBL1489493 | 0.75 | POLB (0.56) | ALDH1A1POLBMAPTHSD17B10KDM4E | |
| SCHEMBL5026343 | 0.74 | ALDH1A1 (0.57) | ALDH1A1POLBMAPTHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555095-B1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2023-04-12 | — | — | EP | disclosed |
| EP-3362451-B1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2023-04-12 | — | — | EP | disclosed |
| CN-110446711-B | Inhibitors of influenza virus replication and uses thereof | 广东东阳光药业有限公司 | 2022-02-15 | — | — | CN | disclosed |
| US-11225477-B2 | Inhibitors of influenza virus replication, application methods and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-01-18 | — | — | US | disclosed |
| US-10987354-B2 | Inhibitors of influenza virus replication and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2021-04-27 | — | — | US | disclosed |
| CN-109748915-B | Inhibitors of influenza virus replication and methods of use and uses thereof | 广东东阳光药业有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-107759571-B | Inhibitors of influenza virus replication and methods of use and uses thereof | 广东东阳光药业有限公司 | 2021-03-02 | — | — | CN | disclosed |
| US-10927118-B2 | Inhibitors of influenza virus replication and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2021-02-23 | — | — | US | disclosed |
| CN-108276401-B | Inhibitors of influenza virus replication and uses thereof | 广东东阳光药业有限公司 | 2020-12-22 | — | — | CN | disclosed |
| US-20200339564-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-10-29 | — | — | US | disclosed |
| CN-108218873-A | Inhibitors of influenza viruses replication and application thereof | 广东东阳光药业有限公司 | 2018-06-29 | — | — | CN | disclosed |
| CN-107759571-A | Inhibitors of influenza viruses replication and its application method and purposes | 广东东阳光药业有限公司 | 2018-03-06 | — | — | CN | disclosed |
| US-20100130473-A1 | COMPOUNDS | HUMMERSONE MARC GEOFFREY | 2010-05-27 | — | — | US | disclosed |
| US-20100130473-A1 | COMPOUNDS | HUMMERSONE MARC GEOFFREY | 2010-05-27 | — | — | US | disclosed |
| US-20100130473-A1 | COMPOUNDS | HUMMERSONE MARC GEOFFREY | 2010-05-27 | — | — | US | disclosed |
| US-7504397-B2 | mTOR inhibitor compounds | KUDOS PHARMACEUTICALS LTD. (GB) | 2009-03-17 | — | — | US | disclosed |
| US-7504397-B2 | mTOR inhibitor compounds | KUDOS PHARMACEUTICALS LTD. (GB) | 2009-03-17 | — | — | US | disclosed |
| EP-1877388-A2 | HYDRAZINOMETHYL, HYDRAZONOMETHYL AND 5-MEMBERED HETEROCYLIC COMPOUNDS WHICH ACT AS MTOR INHIBITORS AND THEIR USE AS ANTI CANCER AGENTS | Kudos Pharmaceuticals Ltd (GB) | 2008-01-16 | — | — | EP | disclosed |
| US-20060199804-A1 | Compounds | KUDOS PHARMACEUTICALS LTD (GB) | 2006-09-07 | — | — | US | disclosed |
| WO-2006090167-A2 | HYDRAZINOMETHYL, HYDR ZONOMETHYL AND 5-MEMBERED HETEROCYLIC COMPOUNDS WHICH ACT AS MTOR INHIBITORS AND THEIR USE AS ANTI CANCER AGENTS | KUDOS PHARMACEUTICALS LIMITED (GB) | 2006-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927118-B2 | Inhibitors of influenza virus replication and uses thereof | EIF2AK2, POLRMT, ZC3HAV1 | ALDH1A1 4038/4885POLB 24/4885MAPT 3563/4885 |
| US-20200339564-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF | EIF2AK2, ZC3HAV1, MAVS | ALDH1A1 3638/4885POLB 38/4885MAPT 4019/4885 |
| US-10987354-B2 | Inhibitors of influenza virus replication and uses thereof | ZC3HAV1, MAVS, POLRMT | ALDH1A1 3909/4885POLB 35/4885MAPT 3480/4885 |
| US-20060199804-A1 | Compounds | CA4, CA6, CYP2B6 | ALDH1A1 1821/4885POLB 3697/4885MAPT 4672/4885 |
| US-11225477-B2 | Inhibitors of influenza virus replication, application methods and uses thereof | POLRMT, EIF2AK2, POLM | ALDH1A1 3790/4885POLB 12/4885MAPT 4252/4885 |
| US-20100130473-A1 | COMPOUNDS | CA6, CYP2B6, CA4 | ALDH1A1 1677/4885POLB 3845/4885MAPT 4601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.