Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.61 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.59 |
| ▸ | FEN1 | P39748 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.55 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.55 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11826852 | 0.86 | ALDH1A1 (0.63) | ALDH1A1LMNAHPGDSLC9A1ERCC5 | |
| SCHEMBL1286218 | 0.85 | ALDH1A1 (0.70) | ALDH1A1LMNAHPGDSLC9A1ERCC5 | |
| SCHEMBL9477105 | 0.83 | ALDH1A1 (0.69) | ALDH1A1LMNAHPGDNPC1RAB9A | |
| SCHEMBL28511353 | 0.83 | PDE4B (0.52) | ALDH1A1LMNAHPGDSMN1; SMN2KDM4E | |
| SCHEMBL28201855 | 0.83 | SLC9A1 (0.59) | ALDH1A1LMNAHPGDSLC9A1PTPN1 | |
| SCHEMBL7118702 | 0.83 | ALDH1A1 (0.69) | ALDH1A1LMNAHPGDSLC9A1ERCC5 | |
| SCHEMBL9477782 | 0.83 | ALDH1A1 (0.69) | ALDH1A1LMNAHPGDSLC9A1ERCC5 | |
| SCHEMBL221022 | 0.82 | ALDH1A1 (0.67) | ALDH1A1LMNAHPGDSLC9A1ERCC5 | |
| SCHEMBL28202414 | 0.81 | ALDH1A1 (0.49) | ALDH1A1LMNAHPGDSLC9A1ERCC5 | |
| SCHEMBL31462930 | 0.81 | ALDH1A1 (0.42) | ALDH1A1LMNAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535371-B | Guanidine-containing phenyl furan carboxamide compound and application thereof | 华南农业大学 | 2025-02-18 | — | — | CN | disclosed |
| CN-116535371-A | Guanidine-containing phenyl furan carboxamide compound and application thereof | 华南农业大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-110294749-B | (S) -1, 3-thiazole phenyl furan thiocarbamate compound and preparation method and application thereof | 华南农业大学 | 2022-01-25 | — | — | CN | disclosed |
| CN-109265452-B | Substituted phenyl furan-2-mercaptothiazoline ketone compounds and preparation method and application thereof | 华南农业大学 | 2021-08-03 | — | — | CN | disclosed |
| CN-110183428-B | Furan thiocarbamate compound containing 1,2,3, 4-tetrazole and preparation method and application thereof | 华南农业大学 | 2021-08-03 | — | — | CN | disclosed |
| CN-107814791-B | Substituted phenyl furan formyl pyrazole compound and preparation method and application thereof | 华南农业大学 | 2021-07-09 | — | — | CN | disclosed |
| CN-107674070-B | Cyanoimine thiazolidine furan carboxamide compound and preparation method and application thereof | 华南农业大学 | 2020-12-29 | — | — | CN | disclosed |
| CN-107535504-B | Application of 1,3, 4-thiadiazole compound in preventing and treating bacterial blight of rice | 华南农业大学 | 2020-10-23 | — | — | CN | disclosed |
| CN-106045982-A | N'-5-(substituted-phenyl)-2-furanmethenyl-5-propyl-1H-pyrazol-3-ethyl formate compound and preparation method and application thereof | 华南农业大学 | 2016-10-26 | — | — | CN | disclosed |
| US-20100130483-A1 | NOVEL DIAZABICYCLIC ARYL DERIVATIVES | NEUROSEARCH A/S (DK) | 2010-05-27 | — | — | US | disclosed |
| US-6015826-A | INSECTICIDES, APHIDICIDES, AND MITICIDES | DOW AGROSCIENCES LLC | 2000-01-18 | — | — | US | disclosed |
| EP-0922043-A1 | PESTICIDAL 3-(SUBSTITUTED PHENYL)-5-(THIENYL OR FURYL)-1,2,4-TRIAZOLES | Dow AgroSciences LLC (US) | 1999-06-16 | — | — | EP | disclosed |
| WO-1998047894-A1 | PESTICIDAL 3-(SUBSTITUTED PHENYL)-5-(THIENYL OR FURYL)-1,2,4-TRIAZOLES | DOW AGROSCIENCES LLC (US) | 1998-10-29 | — | — | WO | disclosed |
| US-5214042-A | Use of 5-phenyl-2-furan esters, amides and ketones as neuroprotective agents | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1993-05-25 | — | — | US | disclosed |
| US-5118708-A | USE OF 5-PHENYL-2-FURAN ESTERS, AMIDES AND KETONES AS NEUROPROTECTIVE AGENTS | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1992-06-02 | — | — | US | disclosed |
| US-5023272-A | Use of 5-phenyl-2-furan esters and amides as antiepileptic agents | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1991-06-11 | — | — | US | disclosed |
| EP-0404231-A1 | The use of 5-phenyl-2 furan esters and amides as antiepileptic agents | Norwich Eaton Pharmaceuticals, Inc. (US) | 1990-12-27 | — | — | EP | disclosed |
| EP-0404233-A2 | Novel use of 5-phenyl-2-furan esters, amides and ketones as neuroprotective agents | Norwich Eaton Pharmaceuticals, Inc. (US) | 1990-12-27 | — | — | EP | disclosed |
| US-4643996-A | 5-phenyl-2-furoic acid hydrazides | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1987-02-17 | — | — | US | disclosed |
| US-4128550-A | 1-Methyl-4-piperidyl 5-phenyl-2-furoates | MORTON-NORWICH PRODUCTS, INC. (US) | 1978-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130483-A1 | NOVEL DIAZABICYCLIC ARYL DERIVATIVES | CHRNA6, CHRNA10, CHRNA2 | ALDH1A1 846/4885LMNA 2513/4885HPGD 1447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.