Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3326397 | 0.86 | GAA (0.37) | GAAMAPK1RXFP1KDM4EALDH1A1 | |
| SCHEMBL5743661 | 0.86 | GAA (0.37) | GAAMAPK1RXFP1KDM4EALDH1A1 | |
| SCHEMBL3326974 | 0.84 | RAPGEF3 (0.34) | GAAMAPK1RXFP1ALDH1A1MAPT | |
| SCHEMBL6576612 | 0.79 | KDM4E (0.31) | GAAKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL2758643 | 0.71 | RAPGEF3 (0.32) | GAAKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2758644 | 0.69 | RAPGEF3 (0.33) | GAAALDH1A1 | |
| SCHEMBL5747293 | 0.69 | MAPT (0.40) | GAAKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6258551 | 0.67 | RAPGEF3 (0.38) | GAAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9192973 | 0.67 | ABCB1 (0.45) | GAAKDM4EALDH1A1MAPT | |
| SCHEMBL6576617 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673956-B2 | INTERMEDIATES (PARTICULARLY 2-(ARYLHYDRAZINO)SUCCINONITRILE COMPOUNDS AND 3-(ARYLHYDRAZONO)PROPIONITRILE DERIVATIVES FOR PESTICIDES, BY REACTING DIALKOXYPROPIONITRILE WITH AN ACID ADDITION SALT OF ARYLHYDRAZINE | AVENTIS AGRICULTURE LTD. (GB) | 2004-01-06 | — | — | US | disclosed |
| US-20020128485-A1 | Processes for preparing pesticidal intermediates | MERIAL LIMITED | 2002-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128485-A1 | Processes for preparing pesticidal intermediates | CBR3, HCN1, SF3A3 | GAA 4790/4885MAPK1 1992/4885RXFP1 1120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.