Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30481033 | 1.00 | ALPL (0.43) | ALPLKDM4EPKMRCE1NQO2 | |
| SCHEMBL9939657 | 0.93 | KDM4E (0.40) | ALPLKDM4EPKMRCE1NQO2 | |
| SCHEMBL115368 | 0.92 | KDM4E (0.40) | ALPLKDM4EPKMRCE1NQO2 | |
| SCHEMBL29442558 | 0.92 | KDM4E (0.40) | ALPLKDM4EPKMRCE1NQO2 | |
| SCHEMBL29423657 | 0.92 | KDM4E (0.40) | ALPLKDM4EPKMRCE1NQO2 | |
| SCHEMBL3327659 | 0.91 | KDM4E (0.39) | ALPLKDM4EPKMRCE1NQO2 | |
| SCHEMBL16047255 | 0.90 | ALPL (0.54) | ALPLKDM4EPKMRCE1NQO2 | |
| SCHEMBL694541 | 0.89 | ALDH1A1 (0.43) | ALPLKDM4ENQO2ALDH1A1HSD17B10 | |
| SCHEMBL3324552 | 0.89 | ALPL (0.44) | ALPLKDM4EPKMRCE1NQO2 | |
| SCHEMBL16047078 | 0.88 | KDM4E (0.39) | ALPLKDM4EPKMRCE1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2060566-B1 | Poly-substituted aryls | DOW AGROSCIENCES LLC (US) | 2016-06-08 | — | — | EP | claimed |
| CN-116003395-A | [1,2,4] oxadiazole pyridine compound and application thereof | 郑州手性药物研究院有限公司 | 2023-04-25 | — | — | CN | disclosed |
| US-10556865-B2 | Synergistic herbicidal composition containing certain pyridine or pyrimidine carboxylic acids and certain cereal and rice herbicides | DOW AGROSCIENCES LLC (US) | 2020-02-11 | — | — | US | disclosed |
| US-20180022703-A1 | SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING CERTAIN PYRIDINE OR PYRIMIDINE CARBOXYLIC ACIDS AND CERTAIN CEREAL AND RICE HERBICIDES | CORTEVA AGRISCIENCE LLC | 2018-01-25 | — | — | US | disclosed |
| EP-2899182-B1 | Arylalkyl esters of 4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2018-01-10 | — | — | EP | disclosed |
| EP-2514314-B1 | Synergistic herbicidal composition containing certain pyridine carboxylic acids and certain cereal and rice herbicides | DOW AGROSCIENCES LLC (US) | 2016-06-15 | — | — | EP | disclosed |
| EP-2060566-B1 | Poly-substituted aryls | DOW AGROSCIENCES LLC (US) | 2016-06-08 | — | — | EP | disclosed |
| US-9169217-B2 | Arylalkyl esters of 4-amino-6-(substituted phenyl)-picolinates and 6-amino-2-(substituted phenyl)-pyrimidinecarboxylates and their use as selective herbicides for crops | DOW AGROSCIENCES LLC (US) | 2015-10-27 | — | — | US | disclosed |
| EP-2926661-A1 | Synergistic herbicidal composition containing certain pyridine carboxylic acids and certain cereal and rice herbicides | Dow AgroSciences LLC (US) | 2015-10-07 | — | — | EP | disclosed |
| EP-2899182-A1 | Arylalkyl esters of 4-aminopicolinates and their use as herbicides | Dow AgroSciences LLC (US) | 2015-07-29 | — | — | EP | disclosed |
| EP-2060566-A1 | Poly-substituted aryls | Dow AgroSciences LLC (US) | 2009-05-20 | — | — | EP | disclosed |
| US-20090062121-A1 | SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING CERTAIN PYRIDINE OR PYRIMIDINE CARBOXYLIC ACIDS AND CERTAIN CEREAL AND RICE HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-03-05 | — | — | US | disclosed |
| WO-2009029518-A2 | SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING CERTAIN PYRIDINE OR PYRIMIDINE CARBOXYLIC ACIDS AND CERTAIN CEREAL AND RICE HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-03-05 | — | — | WO | disclosed |
| US-7498468-B2 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2009-03-03 | — | — | US | disclosed |
| EP-1973881-A2 | 6-(POLY-SUBSTITUTED ARYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | Dow Agrosciences LLC (US) | 2008-10-01 | — | — | EP | disclosed |
| US-20080051596-A1 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2008-02-28 | — | — | US | disclosed |
| US-20080045734-A1 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2008-02-21 | — | — | US | disclosed |
| US-7314849-B2 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2008-01-01 | — | — | US | disclosed |
| US-20070179060-A1 | 6-(Poly-substituted aryl)-4-aminopicolinates and their use as herbicides | CORTEVA AGRISCIENCE LLC | 2007-08-02 | — | — | US | disclosed |
| WO-2007082098-A2 | 6-(POLY-SUBSTITUTED ARYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2007-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045734-A1 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | AAAS, DDT, AADAC | ALPL 3237/4885KDM4E 672/4885PKM 1973/4885 |
| US-10556865-B2 | Synergistic herbicidal composition containing certain pyridine or pyrimidine carboxylic acids and certain cereal and rice herbicides | DHFR, DPYD, DDT | ALPL 3750/4885KDM4E 1949/4885PKM 1157/4885 |
| US-20070179060-A1 | 6-(Poly-substituted aryl)-4-aminopicolinates and their use as herbicides | AAAS, DDT, AADAC | ALPL 3237/4885KDM4E 672/4885PKM 1973/4885 |
| US-20090062121-A1 | SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING CERTAIN PYRIDINE OR PYRIMIDINE CARBOXYLIC ACIDS AND CERTAIN CEREAL AND RICE HERBICIDES | DHFR, DPYD, DDT | ALPL 3750/4885KDM4E 1949/4885PKM 1157/4885 |
| US-20180022703-A1 | SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING CERTAIN PYRIDINE OR PYRIMIDINE CARBOXYLIC ACIDS AND CERTAIN CEREAL AND RICE HERBICIDES | DHFR, DPYD, DDT | ALPL 3750/4885KDM4E 1949/4885PKM 1157/4885 |
| US-20080051596-A1 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | AAAS, DDT, AADAC | ALPL 3237/4885KDM4E 672/4885PKM 1973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.