Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.43 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29833663 | 0.79 | MAOA (0.52) | MAOAALDH1A1KDM4ECYP3A4HPGD | |
| SCHEMBL644478 | 0.79 | MAOA (0.52) | MAOAALDH1A1KDM4ECYP3A4HPGD | |
| SCHEMBL7073740 | 0.76 | MAOA (0.51) | ALOX15IKBKBMAOAPTGS2VKORC1 | |
| SCHEMBL30255441 | 0.72 | MAOA (0.69) | MAOAMGAMALDH1A1LMNAKDM4E | |
| SCHEMBL5612997 | 0.72 | MAOA (0.69) | MAOAMGAMALDH1A1LMNAKDM4E | |
| SCHEMBL2052448 | 0.71 | IKBKB (0.58) | IKBKBMAOAMGAMGAASI | |
| SCHEMBL3130212 | 0.71 | IKBKB (0.61) | IKBKBMAOAPTGS1PTGS2MGAM | |
| SCHEMBL1857089 | 0.70 | ALOX15 (0.52) | ALOX15IKBKBPPARGPTGS1GAA | |
| SCHEMBL7072951 | 0.69 | MAOB (0.45) | ALOX15MAOALMNAKDM4EHPGD | |
| SCHEMBL29287875 | 0.69 | MAOA (0.52) | MAOAALDH1A1LMNAKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137421-A1 | SMALL MOLECULE THERAPEUTICS, SYNTHESIS OF ANALOGUES AND DERIVATIVES AND METHODS OF USE | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2010-06-03 | — | — | US | disclosed |
| WO-2008057604-A9 | SMALL MOLECULE THERAPEUTICS, SYNTHESES OF ANALOGUES AND DERIVATIVES AND METHODS OF USE | UNIV CALIFORNIA (US) | 2008-10-02 | — | — | WO | disclosed |
| WO-2008057604-A2 | SMALL MOLECULE THERAPEUTICS, SYNTHESES OF ANALOGUES AND DERIVATIVES AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137421-A1 | SMALL MOLECULE THERAPEUTICS, SYNTHESIS OF ANALOGUES AND DERIVATIVES AND METHODS OF USE | BAD, CASP3, BID | ALOX15 2223/4885RXRA 3637/4885IKBKB 502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.