SCHEMBL3327005

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3327854	0.88	HTR6 (0.42)	NR1H2RORCFABP4HTR6MET
	SCHEMBL3327338	0.86	HTR6 (0.49)	RORCFABP4HTR6MEN1KMT2A
	SCHEMBL27774809	0.85	FABP4 (0.40)	NR1H2FABP4HTR6MEN1KMT2A
	SCHEMBL3328464	0.85	HTR6 (0.42)	NR1H2RORCFABP4HTR6MET
	SCHEMBL3325097	0.84	HTR6 (0.50)	RORCHTR6
	SCHEMBL28623603	0.81	HTR6 (0.44)	NR1H2FABP4HTR6MEN1KMT2A
	SCHEMBL3325189	0.81	AKR1C3 (0.40)	NR1H2RORCHTR6L3MBTL1
	SCHEMBL3325153	0.80	HTR6 (0.43)	FABP4HTR6MEN1KMT2ACHRM1
	SCHEMBL3325114	0.79	GPR119 (0.40)	HTR6METMEN1KMT2AL3MBTL1
	SCHEMBL3327961	0.79	BRD4 (0.40)	NR1H2RORCHTR6L3MBTL1PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.