Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13361617 | 0.94 | KMT2A (0.56) | KMT2AMEN1SMN1; SMN2POLBP2RX7 | |
| SCHEMBL13333069 | 0.83 | HPGD (0.61) | KMT2AMEN1SMN1; SMN2POLBHSD11B1 | |
| SCHEMBL3323255 | 0.74 | KMT2A (0.60) | KMT2AMEN1SMN1; SMN2POLBP2RX7 | |
| SCHEMBL3327631 | 0.74 | HSD11B1 (0.67) | KMT2AMEN1SMN1; SMN2POLBP2RX7 | |
| SCHEMBL3321995 | 0.73 | P2RX7 (0.74) | KMT2AMEN1SMN1; SMN2POLBP2RX7 | |
| SCHEMBL1520325 | 0.72 | TAAR1 (0.63) | SMN1; SMN2POLBTAAR1TP53MAPT | |
| SCHEMBL3322052 | 0.70 | KMT2A (0.74) | KMT2AMEN1SMN1; SMN2POLBP2RX7 | |
| SCHEMBL3320032 | 0.70 | KMT2A (0.74) | KMT2AMEN1SMN1; SMN2POLBP2RX7 | |
| Adamantane SCHEMBL3322185 | 0.69 | KMT2A (0.72) | KMT2AMEN1SMN1; SMN2POLBP2RX7 | |
| SCHEMBL13361624 | 0.69 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2POLBP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120789-A1 | Compound | STERIX LIMITED (GB) | 2010-05-13 | — | — | US | disclosed |
| US-20100120789-A1 | Compound | STERIX LIMITED (GB) | 2010-05-13 | — | — | US | disclosed |
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | STERIX LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | STERIX LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
| EP-1861384-A1 | 11-BETA-HYDROXYSTEROID DEHYDROGENASE INHIBITORS | Sterix Limited (GB) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006100502-A1 | 11-BETA-HYDROXYSTEROID DEHYDROGENASE INHIBITORS | STERIX LIMITED (GB) | 2006-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | HSD3B1, HSD3B2, HSD11B1 | KMT2A 3083/4885MEN1 3474/4885SMN1; SMN2 4801/4885 |
| US-20100120789-A1 | Compound | NR0B2, NR0B1, NR4A1 | KMT2A 2533/4885MEN1 2608/4885SMN1; SMN2 4612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.