Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | USP2 | O75604 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13175310 | 0.90 | TDP1 (0.41) | TDP1ALDH1A1HSD17B10LMNAGABRR1 | |
| Acetic Acid SCHEMBL8369041 | 0.86 | GABRR1 (0.40) | TDP1ALDH1A1HSD17B10LMNAGABRR1 | |
| SCHEMBL5358516 | 0.83 | TDP1 (0.45) | TDP1ALDH1A1HSD17B10LMNAHPGD | |
| SCHEMBL13459987 | 0.83 | TDP1 (0.45) | TDP1ALDH1A1HSD17B10LMNAHPGD | |
| SCHEMBL8839776 | 0.82 | ALOX15 (0.42) | TDP1ALDH1A1HSD17B10LMNAHPGD | |
| SCHEMBL7185162 | 0.82 | ALDH1A1 (0.41) | TDP1ALDH1A1HSD17B10LMNAKDM4E | |
| SCHEMBL3155490 | 0.79 | GABRP (0.39) | TDP1LMNAGABRR1MAPTMEN1 | |
| SCHEMBL8200830 | 0.77 | LMNA (0.55) | TDP1ALDH1A1LMNAKDM4ECYP3A4 | |
| SCHEMBL8200825 | 0.77 | LMNA (0.55) | TDP1ALDH1A1LMNAKDM4ECYP3A4 | |
| SCHEMBL8201157 | 0.77 | LMNA (0.55) | TDP1ALDH1A1LMNAKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137592-A1 | PROCESS FOR PREPARING PURINE DERIVATIVE | AUROBINDO PHARMA LTD (IN) | 2010-06-03 | — | — | US | disclosed |
| EP-2170840-A1 | AN IMPROVED PROCESS FOR PREPARING PURINE DERIVATIVE | Aurobindo Pharma Ltd (IN) | 2010-04-07 | — | — | EP | disclosed |
| WO-2008155613-A1 | AN IMPROVED PROCESS FOR PREPARING PURINE DERIVATIVE | AUROBINDO PHARMA LTD (IN) | 2008-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137592-A1 | PROCESS FOR PREPARING PURINE DERIVATIVE | TYMP, PNP, UMPS | TDP1 407/4885ALDH1A1 1898/4885HSD17B10 3220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.