Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2474607 | 0.77 | TTR (0.55) | MAOAMAOBCDC25BCYP3A4TSHR | |
| SCHEMBL11865351 | 0.77 | ALDH1A1 (0.50) | MAOAMAOBCDC25BCYP3A4TSHR | |
| SCHEMBL28151567 | 0.76 | LRRK2 (0.38) | MAOAMAOBCDC25BCYP3A4TSHR | |
| SCHEMBL4199767 | 0.74 | CES1 (0.57) | MAOAMAOBMAPTMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29591677 | 0.73 | CES1 (0.55) | MAOAMAOBMAPTMAPK1ALDH1A1 | |
| SCHEMBL17667418 | 0.72 | PARK7 (0.53) | MAOAMAOBCDC25BMAPTCASP1 | |
| SCHEMBL29407915 | 0.72 | PARK7 (0.53) | MAOAMAOBCDC25BMAPTCASP1 | |
| SCHEMBL20254407 | 0.70 | ACHE (0.54) | MAOAMAOBMAPTTP53SMN1; SMN2 | |
| SCHEMBL22667213 | 0.69 | CUL4A (0.51) | ALDH1A1IDO1CA1CA2CASP3 | |
| SCHEMBL30404657 | 0.69 | CUL4A (0.51) | ALDH1A1IDO1CA1CA2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8642765-B2 | Azaindole-indole coupled derivatives, preparation methods and uses thereof | Cheng, Jingcai (CN) | 2014-02-04 | — | — | US | disclosed |
| US-20100137356-A1 | AZAINDOLE-INDOLE COUPLED DERIVATIVES, PREPARATION METHODS AND USES THEREOF | Cheng, Jingcai (CN) | 2010-06-03 | — | — | US | disclosed |
| EP-2168964-A1 | AZAINDOLE-INDOLE COUPLED DERIVATIVES, PREPARATION METHODS AND USES THEREOF | Cheng, Jingcai (CN) | 2010-03-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137356-A1 | AZAINDOLE-INDOLE COUPLED DERIVATIVES, PREPARATION METHODS AND USES THEREOF | IDO1, IDO2, INMT | MAOA 78/4885MAOB 88/4885CDC25B 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.