SCHEMBL333081

SCHEMBL333081

NS.c1cc(C2CCCCC2)c2nc(C3CCCCC3)sc2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.34
ALDH1A1 P00352 3/20 0.34
GAA P10253 2/20 0.34
ADORA3 P0DMS8 2/20 0.34
UBE2M P61081 3/20 0.33
DCUN1D1 Q96GG9 3/20 0.33
MKNK1 Q9BUB5 2/20 0.33
LMNA P02545 2/20 0.33
POLB P06746 1/20 0.33
MAPK1 P28482 1/20 0.33
BTK Q06187 1/20 0.33
RAB9A P51151 2/20 0.32
HPGD P15428 1/20 0.32
NPC1 O15118 1/20 0.32
TSHR P16473 1/20 0.32
CASP3 P42574 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4673792 0.95 KMT2A (0.42) KMT2AMEN1SMN1; SMN2ALDH1A1GAA
SCHEMBL28471930 0.90 KMT2A (0.37) KMT2AMEN1SMN1; SMN2ALDH1A1GAA
SCHEMBL20305613 0.82 LMNA (0.50) SMN1; SMN2ALDH1A1GAALMNAPOLB
SCHEMBL357736 0.78 TXN (0.39) KMT2AMEN1SMN1; SMN2ALDH1A1LMNA
SCHEMBL540891 0.77 CA2 (0.48)
SCHEMBL29690686 0.77 LMNA (0.51) KMT2AMEN1SMN1; SMN2ALDH1A1GAA
SCHEMBL1933693 0.76 TDO2 (0.32) SMN1; SMN2ALDH1A1POLBRAB9AHPGD
SCHEMBL8969250 0.73 CNR1 (0.36) KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A
SCHEMBL816962 0.71 KMT2A (0.71) KMT2AMEN1SMN1; SMN2ALDH1A1GAA
SCHEMBL28919884 0.71 KMT2A (0.71) KMT2AMEN1SMN1; SMN2ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118139919-A Elastomeric products 大陆轮胎德国有限公司 2024-06-04 CN claimed
EP-4276146-A1 COMMERCIAL VEHICLE TYRE Continental Reifen Deutschland GmbH (DE) 2023-11-15 EP claimed
CN-113166300-B Sulfur-modified chloroprene rubber, method for producing same, sulfur-modified chloroprene rubber composition, sulfide, and molded article 电化株式会社 2023-09-15 CN claimed
CN-113166301-B Sulfur-modified chloroprene rubber, method for producing same, sulfur-modified chloroprene rubber composition, sulfide, and molded article 电化株式会社 2023-07-14 CN claimed
CN-116323683-A Foam rubber composition, foam, and molded article 电化株式会社 2023-06-23 CN claimed
CN-113661181-B Sulfur-modified chloroprene rubber and method for producing same, sulfur-modified chloroprene rubber composition, vulcanizate, and molded article 电化株式会社 2023-03-14 CN claimed
CN-114479217-B Low rolling resistance and high wet-skid resistance solution-polymerized styrene-butadiene rubber composite material as well as preparation method and application thereof 北京化工大学 2023-02-28 CN claimed
CN-115594896-A Rubber composition, rubber product and application 北京彤程创展科技有限公司(CN) 2023-01-13 CN claimed
CN-115572417-A X-waveband light rubber wave-absorbing material and preparation method thereof 青岛科技大学 2023-01-06 CN claimed
CN-112321952-B Ethylene propylene diene monomer composite rubber material and preparation method thereof 中物院成都科学技术发展中心 2022-12-20 CN claimed
US-20090054595-A1 Compounding Formulations for Producing Articles from Guayule Natural Rubber YULEX CORPORATION 2009-02-26 US claimed
EP-1226040-B1 TIRE FOR VEHICLES HAVING A HIGH WEAR RESISTANCE AND VULCANIZABLE RUBBER COMPOSITION FOR MAKING THE SAME PIRELLI (IT) 2008-11-19 EP claimed
WO-2008082267-A1 METHOD FOR PRODUCTION OF POLYARYLENE SULFIDE RESIN WITH EXCELLENT LUMINOSITY AND THE POLYARYLENE SULFIDE RESIN SK CHEMICALS CO., LTD. (KR) 2008-07-10 WO claimed
WO-2008023915-A1 MANUFACTURING PROCESS FOR POLY(ARYLENE SULFIDE) SK CHEMICALS CO., LTD. (KR) 2008-02-28 WO claimed
US-20070093612-A1 Composition, cured article, and associated method GENERAL ELECTRIC COMPANY (US) 2007-04-26 US claimed
EP-0732362-B1 Silica reinforced rubber composition and use in tyres GOODYEAR TIRE & RUBBER (US) 1999-06-02 EP claimed
EP-0845493-A1 Silica reinforced rubber composition and use in tires THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-06-03 EP claimed
US-5674932-A THERMOMECHANICALLY MIXING A SULFUR VULCANIZABLE ELASTOMER, A PARTICULATE FILLER OF SILICA, ALUMINA OR SILICA-ALUMINA, AN ORGANOSILANE DISULFIDE/TRISULFIDE COMPOUND, ELEMENTAL SULFUR OR A SULFUR SOURCE AND AN ACCELERATOR THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-10-07 US claimed
US-5580919-A ORGANOSILANE DISULFIDE COUPLER THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-12-03 US claimed
EP-0732362-A1 Silica reinforced rubber composition and use in tyres THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-09-18 EP claimed