SCHEMBL4673792

SCHEMBL4673792

c1cc(C2CCCCC2)c2nc(C3CCCCC3)sc2c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.36
ALDH1A1 P00352 3/20 0.36
GAA P10253 2/20 0.36
ADORA3 P0DMS8 2/20 0.36
UBE2M P61081 4/20 0.34
DCUN1D1 Q96GG9 4/20 0.34
LMNA P02545 3/20 0.34
POLB P06746 2/20 0.34
MAPK1 P28482 1/20 0.34
MKNK1 Q9BUB5 2/20 0.34
RAB9A P51151 2/20 0.34
HPGD P15428 2/20 0.34
CASP3 P42574 2/20 0.34
SENP7 Q9BQF6 2/20 0.34
SENP6 Q9GZR1 2/20 0.34
NPC1 O15118 1/20 0.34
TSHR P16473 1/20 0.34
SENP8 Q96LD8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL333081 0.95 KMT2A (0.39) KMT2AMEN1SMN1; SMN2ALDH1A1GAA
SCHEMBL28471930 0.92 KMT2A (0.37) KMT2AMEN1SMN1; SMN2ALDH1A1GAA
SCHEMBL20305613 0.83 LMNA (0.50) SMN1; SMN2ALDH1A1GAALMNAPOLB
SCHEMBL29690686 0.81 LMNA (0.51) KMT2AMEN1SMN1; SMN2ALDH1A1GAA
SCHEMBL357736 0.79 TXN (0.39) KMT2AMEN1SMN1; SMN2ALDH1A1LMNA
SCHEMBL540891 0.78 CA2 (0.48)
SCHEMBL8969250 0.77 CNR1 (0.36) KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A
SCHEMBL1933693 0.77 TDO2 (0.32) SMN1; SMN2ALDH1A1POLBRAB9AHPGD
SCHEMBL816962 0.75 KMT2A (0.71) KMT2AMEN1SMN1; SMN2ALDH1A1GAA
SCHEMBL30702394 0.75 KMT2A (0.71) KMT2AMEN1SMN1; SMN2ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105916884-B Hydrogenated nitrile rubber containing phosphine oxide or diphosphine oxide 阿朗新科德国有限责任公司 2017-10-03 CN claimed
EP-1514701-B1 PROCESS FOR PRODUCING PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2008-11-26 EP claimed
EP-4232950-A1 RADIO FREQUENCY COMMUNICATION MODULE COMPRISING AN ELECTRONIC DEVICE COATED IN AN ELASTOMERIC MATERIAL COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2023-08-30 EP disclosed
CN-110272568-B Phenolic resin composition and use thereof in rubber compositions for reducing hysteresis SI集团有限公司 2023-05-12 CN disclosed
CN-113454153-B In-line ultrasonic inspection for detecting partial vulcanization of rubber mixtures in-situ silylation of light-colored fillers 朗盛德国有限责任公司 2023-04-28 CN disclosed
EP-4055100-A1 RUBBER COMPOSITION COMPRISING A SUITABLE FILLER AND A SUITABLE CROSSLINKING SYSTEM COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2022-09-14 EP disclosed
WO-2022084608-A1 RADIO FREQUENCY COMMUNICATION MODULE COMPRISING AN ELECTRONIC DEVICE COATED IN AN ELASTOMERIC MATERIAL COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2022-04-28 WO disclosed
CN-110809523-A Reinforcing member for tire and tire using same 株式会社普利司通 2020-02-18 CN disclosed
WO-2020011009-A1 RUBBER COMPOSITION, AND TIRE USING THE SAME 杭州星庐科技有限公司 2020-01-16 WO disclosed
CN-105670130-B Comprehensive promotor of a kind of rubber and preparation method thereof 永嘉县伟诚橡胶工贸有限公司 2019-02-05 CN disclosed
CN-108603000-A METHOD FOR TESTING IN SITU SILANIZATION OF BRIGHT FILLERS 朗盛德国有限责任公司 2018-09-28 CN disclosed
WO-2007054228-A2 SULFUR-CROSSLINKED HYDROGENATED VINYL POLYBUTADIENES, AND USE THEREOF FOR THE PRODUCTION OF TECHNICAL RUBBER ARTICLES HAVING GOOD RECOVERY BEHAVIOR ACROSS A LARGE TEMPERATURE RANGE LANXESS DEUTSCHLAND GMBH (DE) 2007-05-18 WO disclosed
CN-1690120-A Resin compositions with high vibration damping ability MITSUBISHI GAS CHEMICAL CO (JP) 2005-11-02 CN disclosed
US-6539996-B1 Tire with sidewall rubber insert THE GOODYEAR TIRE & RUBBER COMPANY 2003-04-01 US disclosed
EP-1038697-B1 Tire with sidewall rubber insert GOODYEAR TIRE & RUBBER (US) 2003-03-05 EP disclosed
US-6202726-B1 Tire with sidewall rubber insert THE GOODYEAR TIRE & RUBBER COMPANY 2001-03-20 US disclosed
EP-1038697-A1 Tire with sidewall rubber insert THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-09-27 EP disclosed
US-4935297-A BISMALEIMIDE MODIFIED RUBBERS, PHENOLIC RESINS AND AMINO RESINS BRIDGESTONE CORPORATION (JP) 1990-06-19 US disclosed
EP-0160634-B1 METAL COMPLEXES USEFUL AS RUBBER/METAL BONDING PROMOTERS MONSANTO EUROPE S.A./N.V. (BE) 1989-07-05 EP disclosed
CN-86102520-A Contain improving one's methods of sulphenamide activated stock performance 1988-04-13 CN disclosed