Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 5/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL951786 | 0.91 | HSD11B1 (0.63) | ALDH1A1GAAHSD11B1TSHRCTSK | |
| SCHEMBL29727241 | 0.89 | KMT2A (0.60) | ALDH1A1GAAHSD11B1TSHRCTSK | |
| SCHEMBL951534 | 0.87 | HSD11B1 (0.60) | ALDH1A1GAAHSD11B1TSHRCTSK | |
| SCHEMBL30135990 | 0.86 | CTSL (0.49) | ALDH1A1GAAHSD11B1TSHRCTSK | |
| SCHEMBL19212197 | 0.86 | DPP4 (0.48) | ALDH1A1GAAHSD11B1TSHRCTSK | |
| SCHEMBL2734467 | 0.85 | HSD11B1 (0.53) | ALDH1A1GAAHSD11B1TSHRCTSK | |
| SCHEMBL954965 | 0.84 | KMT2A (0.60) | ALDH1A1GAAHSD11B1TSHRCTSK | |
| SCHEMBL30135994 | 0.82 | MEN1 (0.52) | ALDH1A1GAAHSD11B1TSHRCTSK | |
| SCHEMBL30060706 | 0.81 | LMNA (0.51) | ALDH1A1GAATSHRCTSLCYP3A4 | |
| SCHEMBL17082722 | 0.81 | ALDH1A1 (0.59) | ALDH1A1GAAHSD11B1TSHRCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8669266-B2 | Quinoline-carboxamide derivatives as P2Y12 antagonists | SANOFI (FR) | 2014-03-11 | — | — | US | disclosed |
| US-20100135999-A1 | QUINOLINE-CARBOXAMIDE DERIVATIVES AS P2Y12 ANTAGONISTS | SANOFI-AVENTIS (FR) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100135999-A1 | QUINOLINE-CARBOXAMIDE DERIVATIVES AS P2Y12 ANTAGONISTS | P2RY12, P2RY1, P2RY2 | ALDH1A1 2297/4885GAA 1331/4885HSD11B1 4736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.