SCHEMBL3337265

SCHEMBL3337265

CCO[Si](C)(CCc1ccccc1CCl)OCC

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3341059 0.84 CYP4F2 (0.33) CYP4F2CYP4A11ALDH1A1TSHR
SCHEMBL3339281 0.82 MTNR1A (0.33) ALDH1A1TSHR
SCHEMBL1637617 0.80 CYP4F2 (0.38) CYP4F2CYP4A11
SCHEMBL9860003 0.78 SLC6A4 (0.35) ALDH1A1
SCHEMBL4849033 0.76 ALDH1A1 (0.34) ALDH1A1TSHR
SCHEMBL2144177 0.76 ALDH1A1 (0.34) ALDH1A1TSHR
SCHEMBL9860017 0.76
SCHEMBL929249 0.75 CYP4F2 (0.32) CYP4F2CYP4A11
SCHEMBL8347602 0.74 TP53 (0.31)
SCHEMBL11848934 0.74 ALDH1A1 (0.33) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968458-B2 Composition for resist underlayer film and process for producing same JSR CORPORATION (JP) 2015-03-03 US disclosed
US-8808446-B2 Composition for resist underlayer film and process for producing same JSR CORPORATION (JP) 2014-08-19 US disclosed
US-20100151384-A1 COMPOSITION FOR RESIST UNDERLAYER FILM AND PROCESS FOR PRODUCING SAME JSR CORPORATION (JP) 2010-06-17 US disclosed
US-20090050020-A1 COMPOSITION FOR RESIST UNDERLAYER FILM AND PROCESS FOR PRODUCING SAME JSR CORPORATION (JP) 2009-02-26 US disclosed
EP-1855159-A1 COMPOSITION FOR UNDERLAYER FILM OF RESIST AND PROCESS FOR PRODUCING THE SAME JSR Corporation (JP) 2007-11-14 EP disclosed