Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.33 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 5/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dihydrolipoic Acid SCHEMBL4761909 | 0.98 | NFKB1 (0.38) | NFKB1CA1GSTK1GPR84ENPEP | |
| Dihydrolipoic Acid SCHEMBL1659440 | 0.96 | NFKB1 (0.39) | NFKB1CA1GSTK1GPR84ENPEP | |
| Dihydrolipoic Acid SCHEMBL718014 | 0.96 | NFKB1 (0.43) | NFKB1CA1GSTK1GPR84ENPEP | |
| Dihydrolipoic Acid SCHEMBL5827361 | 0.96 | NFKB1 (0.39) | NFKB1CA1GSTK1GPR84ENPEP | |
| Dihydrolipoic Acid SCHEMBL4094129 | 0.89 | GSTK1 (0.46) | NFKB1GSTK1ENPEPFOLH1 | |
| Zinc Ion SCHEMBL3337795 | 0.86 | HDAC3 (0.36) | NFKB1 | |
| Zinc Ion SCHEMBL3337707 | 0.84 | HDAC3 (0.41) | — | |
| Zinc Ion SCHEMBL2580314 | 0.84 | HDAC3 (0.35) | NFKB1 | |
| Zinc Ion SCHEMBL2583379 | 0.83 | HDAC3 (0.40) | — | |
| SCHEMBL3276879 | 0.82 | HDAC3 (0.36) | NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060122100-A1 | Melanin extinguisher | OGA RESEARCH, INCORPORATED (JP) | 2006-06-08 | — | — | US | claimed |
| EP-1547590-A1 | MELANIN EXTINGUISHER | Oga Research, Incorporated (JP) | 2005-06-29 | — | — | EP | claimed |
| US-8048911-B2 | Melanin eliminator preparation | OGA Research, Inc. (JP) | 2011-11-01 | — | — | US | disclosed |
| US-20090093541-A1 | MELANIN ELIMINATOR PREPARATION | OGA RESEARCH, INC (JP) | 2009-04-09 | — | — | US | disclosed |
| JP-2006206561-A | STABILIZATION OF LIPOIC ACID DERIVATIVE-CONTAINING AQUEOUS PREPARATION | IWAKI KK | 2006-08-10 | — | — | JP | disclosed |
| US-20060122100-A1 | Melanin extinguisher | OGA RESEARCH, INCORPORATED (JP) | 2006-06-08 | — | — | US | disclosed |
| EP-1547590-A1 | MELANIN EXTINGUISHER | Oga Research, Incorporated (JP) | 2005-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122100-A1 | Melanin extinguisher | TYR, MC1R, MITF | NFKB1 2770/4885CA1 4152/4885GSTK1 2911/4885 |
| US-20090093541-A1 | MELANIN ELIMINATOR PREPARATION | TYR, MC1R, MCHR1 | NFKB1 4004/4885CA1 4071/4885GSTK1 3045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.