Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | ALB | P02768 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL785156 | 0.98 | TSHR (0.61) | TSHRALBALDH1A1CES2CES1 | |
| SCHEMBL7080990 | 0.84 | CES2 (0.61) | TSHRALBALDH1A1CES2CES1 | |
| SCHEMBL1614730 | 0.84 | TSHR (0.77) | TSHRALBALDH1A1ALOX15PDK1 | |
| SCHEMBL25216818 | 0.83 | TSHR (0.46) | TSHRALBALDH1A1CES2CES1 | |
| SCHEMBL4442608 | 0.83 | CES2 (0.48) | TSHRALBALDH1A1CES2CES1 | |
| SCHEMBL23079123 | 0.83 | CES2 (0.48) | TSHRALBALDH1A1CES2CES1 | |
| SCHEMBL785155 | 0.83 | ALDH1A1 (0.65) | TSHRALBALDH1A1CES2CES1 | |
| Hydrochloric Acid SCHEMBL11483376 | 0.81 | TSHR (0.74) | TSHRALBALDH1A1ALOX15PDK1 | |
| Hydrochloric Acid SCHEMBL21808814 | 0.81 | TSHR (0.74) | TSHRALBALDH1A1ALOX15PDK1 | |
| SCHEMBL8829671 | 0.81 | TSHR (0.61) | TSHRALBALDH1A1SMN1; SMN2GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 381 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3551634-A1 | SUBSTITUTED PYRAZOLOAZEPIN-8-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | Leo Pharma A/S (DK) | 2019-10-16 | — | — | EP | claimed |
| WO-2018108231-A1 | SUBSTITUTED PYRAZOLOAZEPIN-8-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | LEO PHARMA A/S (DK) | 2018-06-21 | — | — | WO | claimed |
| WO-2018057219-A1 | METHOD OF ALLOCATING INDIVIDUAL OIL OR WATER PRODUCTION CONTRIBUTIONS FROM MULTIPLE COMBINED SOURCES | SPECTRUM TRACER SERVICES, LLC (US) | 2018-03-29 | — | — | WO | claimed |
| US-20180080314-A1 | METHOD OF ALLOCATING INDIVIDUAL OIL OR WATER PRODUCTION CONTRIBUTIONS FROM MULTIPLE COMBINED SOURCES | SPECTRUM TRACER SERVICES, LLC | 2018-03-22 | — | — | US | claimed |
| EP-4746972-A1 | DEUTERATED PARP1 INHIBITOR COMPOUNDS | Duke Street Bio Limited (GB) | 2026-05-27 | — | — | EP | disclosed |
| US-12501829-B2 | Compound for organic optoelectronic device, composition for organic optoelectronic device, organic optoelectronic device, and display device | SAMSUNG SDI CO., LTD. (KR) | 2025-12-16 | — | — | US | disclosed |
| US-20250282791-A1 | PYRAZINE DERIVATIVE AND APPLICATION THEREOF IN INHIBITING SHP2 | SUZHOU GENHOUSE PHARMACEUTICAL CO., LTD (CN) | 2025-09-11 | — | — | US | disclosed |
| US-20250241915-A1 | COMPOUNDS FOR THE TREATMENT OF BRAF-ASSOCIATED DISEASES AND DISORDERS | PFIZER INC. (US) | 2025-07-31 | — | — | US | disclosed |
| US-20250236608-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION | 2025-07-24 | — | — | US | disclosed |
| US-20250228239-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2025-07-17 | — | — | US | disclosed |
| US-12338241-B2 | Bicyclic sulfones and sulfoxides and methods of use thereof | GENENTECH, INC. (US) | 2025-06-24 | — | — | US | disclosed |
| US-12338246-B2 | Pyrazine derivative and application thereof in inhibiting SHP2 | SUZHOU GENHOUSE PHARMACEUTICAL CO., LTD. (CN) | 2025-06-24 | — | — | US | disclosed |
| US-6258838-B1 | Compounds | ASTRAZENECA AB (SE) | 2001-07-10 | — | — | US | disclosed |
| US-20010003121-A1 | Novel compounds | ASTRAZENECA UK LIMITED | 2001-06-07 | — | — | US | disclosed |
| US-6201024-B1 | EFFECTIVE P2X7 RECEPTOR ANTAGONISTS FOR USE IN THE TREATMENT OF INFLAMMATORY, IMMUNE OR CARDIOVASCULAR DISORDERS | ASTRAZENECA UK LIMITED (GB) | 2001-03-13 | — | — | US | disclosed |
| CN-1284057-A | Adamantane derivatives | ASTRA ZENECA BRITISH LTD (GB) | 2001-02-14 | — | — | CN | disclosed |
| EP-1036059-A1 | ADAMANTANE DERIVATIVES | AstraZeneca UK Limited (GB) | 2000-09-20 | — | — | EP | disclosed |
| JP-2000247980-A | PRODUCTION OF (-)PYRIDOBENZOXAZINECARBOXYLIC ACID DERIVATIVE | SAMSUNG ELECTRONICS CO LTD | 2000-09-12 | — | — | JP | disclosed |
| WO-1999029661-A1 | ADAMANTANE DERIVATIVES | ASTRAZENECA UK LIMITED (GB) | 1999-06-17 | — | — | WO | disclosed |
| US-5334753-A | Lithiating halobenzoic acid, then reacting with electrophilic reagent | RHONE-POULENC AGRICULTURE LTD (GB) | 1994-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250241915-A1 | COMPOUNDS FOR THE TREATMENT OF BRAF-ASSOCIATED DISEASES AND DISORDERS | BRAF, NRAS, RAF1 | TSHR 218/4885ALB 4179/4885ALDH1A1 1187/4885 |
| US-12338246-B2 | Pyrazine derivative and application thereof in inhibiting SHP2 | PTPN5, PTPN1, PTPN7 | TSHR 494/4885ALB 3128/4885ALDH1A1 2569/4885 |
| US-12338241-B2 | Bicyclic sulfones and sulfoxides and methods of use thereof | RB1, CCNE2, RPS3A | TSHR 2564/4885ALB 4106/4885ALDH1A1 1912/4885 |
| US-20250282791-A1 | PYRAZINE DERIVATIVE AND APPLICATION THEREOF IN INHIBITING SHP2 | PTPN3, PTPN5, PTPN13 | TSHR 570/4885ALB 2672/4885ALDH1A1 3079/4885 |
| US-20250236608-A1 | EGFR INHIBITORS | EGFR, ERBB2, ERBB3 | TSHR 976/4885ALB 2491/4885ALDH1A1 2147/4885 |
| US-12501829-B2 | Compound for organic optoelectronic device, composition for organic optoelectronic device, organic optoelectronic device, and display device | OCIAD2, OCIAD1, OXER1 | TSHR 4049/4885ALB 2134/4885ALDH1A1 116/4885 |
| US-20250228239-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | ACHE, DDT, MLYCD | TSHR 3383/4885ALB 4212/4885ALDH1A1 443/4885 |
| US-20010003121-A1 | Novel compounds | APP, BACE1, CHRNA5 | TSHR 3980/4885ALB 2411/4885ALDH1A1 1215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.