Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8495708 | 0.80 | SOAT2 (0.38) | RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL8494899 | 0.80 | SOAT2 (0.38) | RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL8496903 | 0.80 | SOAT2 (0.38) | RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL8494857 | 0.80 | SOAT2 (0.38) | RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL8496224 | 0.80 | SOAT2 (0.38) | RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL8495165 | 0.80 | SOAT2 (0.38) | RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL285279 | 0.79 | NPC1 (0.58) | RAB9ANPC1GAAMEN1KMT2A | |
| SCHEMBL29384819 | 0.79 | NPC1 (0.58) | RAB9ANPC1GAAMEN1KMT2A | |
| SCHEMBL5597215 | 0.74 | NPC1 (0.57) | RAB9ANPC1GAAMEN1KMT2A | |
| SCHEMBL2724360 | 0.70 | NPC1 (0.49) | RAB9ANPC1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230131507-A1 | BIOACTIVE POLYMERS FOR OPHTHALMIC APPLICATIONS | KEY MEDICAL TECH INC (US) | 2023-04-27 | — | — | US | disclosed |
| US-20200087433-A1 | NANOHYBRID POLYMERS FOR OPHTHALMIC APPLICATIONS | KEY MEDICAL TECH INC (US) | 2020-03-19 | — | — | US | disclosed |
| US-20130231449-A1 | NANOHYBRID POLYMERS FOR OPHTHALMIC APPLICATIONS | KEY MEDICAL TECHNOLOGIES, INC. (US) | 2013-09-05 | — | — | US | disclosed |
| EP-1828270-B1 | NANOHYBRID POLYMERS FOR OPHTHALMIC APPLICATIONS | KEY MEDICAL TECHNOLOGIES INC (US) | 2013-04-10 | — | — | EP | disclosed |
| US-7745555-B2 | Making high refractive index copolymer by sonicating mixture of carbazole or naphthyl moiety, naphthyl group monomer, hydrophobic monomer, hydrophillic monomer, and crosslinker; soft, optically transparent, high refractive index materials particularly suited for use in intraocular, contact lenses | KEY MEDICAL TECHNOLOGIES, INC. (US) | 2010-06-29 | — | — | US | disclosed |
| US-20080064840-A1 | Making high refractive index copolymer by sonicating mixture of carbazole or naphthyl moiety, naphthyl group monomer, hydrophobic monomer, hydrophillic monomer, and crosslinker; soft, optically transparent, high refractive index materials particularly suited for use in intraocular, contact lenses | MENTAK KHALID | 2008-03-13 | — | — | US | disclosed |
| EP-1828270-A2 | NANOHYBRID POLYMERS FOR OPHTHALMIC APPLICATIONS | Key Medical Technologies, Inc. (US) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006063139-A2 | NANOHYBRID POLYMERS FOR OPHTHALMIC APPLICATIONS | KEY MEDICAL TECHNOLOGIES, INC. (US) | 2006-06-15 | — | — | WO | disclosed |