Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | CES2 | O00748 | 2/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1295300 | 0.95 | GPR84 (0.59) | GPR84FFAR1CES2FFAR4CES1 | |
| SCHEMBL7768831 | 0.93 | GPR84 (0.63) | GPR84FFAR1CES2FFAR4CES1 | |
| SCHEMBL11271581 | 0.93 | GPR84 (0.63) | GPR84FFAR1CES2FFAR4CES1 | |
| SCHEMBL11798444 | 0.93 | GPR84 (0.63) | GPR84FFAR1CES2FFAR4CES1 | |
| SCHEMBL10490506 | 0.93 | GPR84 (0.63) | GPR84FFAR1CES2FFAR4CES1 | |
| SCHEMBL5610620 | 0.93 | GPR84 (0.63) | GPR84FFAR1CES2FFAR4CES1 | |
| SCHEMBL1148737 | 0.93 | GPR84 (0.63) | GPR84FFAR1CES2FFAR4CES1 | |
| Charcoal, Activated SCHEMBL7765415 | 0.93 | GPR84 (0.57) | GPR84FFAR1CES2FFAR4 | |
| SCHEMBL11750658 | 0.93 | GPR84 (0.63) | GPR84FFAR1CES2FFAR4CES1 | |
| SCHEMBL3424708 | 0.93 | GPR84 (0.63) | GPR84FFAR1CES2FFAR4CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426846-A1 | FLUORINATED-AROMATIC SULFONIC ACID CATALYST, PROCESS FOR ITS PRODUCTION, AND ITS USE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-05-15 | — | — | EP | claimed |
| CN-1040332-A | Fluorine-containing aromatic sulfonic acid catalyzer and method for making and purposes | MITSUI PETROCHEMICAL IND (JP) | 1990-03-14 | — | — | CN | claimed |
| JP-2111739-A | — | — | None | — | — | JP | disclosed |
| US-20140171444-A1 | Inhibitors of Mycobacterium Tuberculosis Malate Synthase, Methods of Making and Uses Thereof | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2014-06-19 | — | — | US | disclosed |
| US-8664255-B2 | Inhibitors of mycobacterium tuberculosis malate synthase, methods of making and uses thereof | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2014-03-04 | — | — | US | disclosed |
| US-20100113477-A1 | Inhibitors of mycobacterium tuberculosis malate synthase, methods of making and uses thereof | TEXAS A&M UNIVERSITY SYSTEM, THE | 2010-05-06 | — | — | US | disclosed |
| WO-2010047774-A2 | INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS MALATE SYNTHASE, METHODS OF MARKING AND USES THEREOF | THE TEXAS A & M UNIVERSITY SYSTEM (US) | 2010-04-29 | — | — | WO | disclosed |
| EP-0426846-A1 | FLUORINATED-AROMATIC SULFONIC ACID CATALYST, PROCESS FOR ITS PRODUCTION, AND ITS USE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-05-15 | — | — | EP | disclosed |
| JP-H02111739-A | PREPARATION OF HYDROXYARYL ARYL KETONES | MITSUI PETROCHEM IND LTD | 1990-04-24 | — | — | JP | disclosed |
| CN-1040332-A | Fluorine-containing aromatic sulfonic acid catalyzer and method for making and purposes | MITSUI PETROCHEMICAL IND (JP) | 1990-03-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113477-A1 | Inhibitors of mycobacterium tuberculosis malate synthase, methods of making and uses thereof | ME3, ME1, MDH1 | GPR84 3153/4885FFAR1 2989/4885CES2 1884/4885 |
| US-20140171444-A1 | Inhibitors of Mycobacterium Tuberculosis Malate Synthase, Methods of Making and Uses Thereof | ME3, ME1, MDH1 | GPR84 3153/4885FFAR1 2989/4885CES2 1884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.