Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18216997 | 0.89 | KMT2A (0.44) | KMT2ASMN1; SMN2NPSR1MEN1PKM | |
| SCHEMBL3342807 | 0.88 | KMT2A (0.43) | KMT2ASMN1; SMN2NPSR1MEN1PKM | |
| SCHEMBL13305899 | 0.87 | NPSR1 (0.45) | KMT2ASMN1; SMN2NPSR1MEN1PKM | |
| SCHEMBL13305888 | 0.86 | KMT2A (0.41) | KMT2ASMN1; SMN2NPSR1MEN1PKM | |
| SCHEMBL16093068 | 0.81 | KMT2A (0.50) | KMT2ASMN1; SMN2NPSR1MEN1PKM | |
| SCHEMBL13305925 | 0.79 | PKM (0.39) | KMT2ASMN1; SMN2MEN1PKMHDAC3 | |
| SCHEMBL13305931 | 0.78 | LMNA (0.42) | KMT2AMEN1PKMMAPTHDAC3 | |
| SCHEMBL2893483 | 0.77 | KMT2A (0.51) | KMT2ASMN1; SMN2NPSR1MEN1CYP3A4 | |
| SCHEMBL237873 | 0.77 | KMT2A (0.51) | KMT2ASMN1; SMN2NPSR1MEN1CYP3A4 | |
| Propane SCHEMBL3346178 | 0.76 | KMT2A (0.47) | KMT2ASMN1; SMN2NPSR1MEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160574-A1 | Polymerisation Using Chain Transfer Agents | THE UNIVERSITY OF LEEDS (GB) | 2010-06-24 | — | — | US | disclosed |
| US-20100160574-A1 | Polymerisation Using Chain Transfer Agents | THE UNIVERSITY OF LEEDS (GB) | 2010-06-24 | — | — | US | disclosed |
| US-20100160574-A1 | Polymerisation Using Chain Transfer Agents | THE UNIVERSITY OF LEEDS (GB) | 2010-06-24 | — | — | US | disclosed |
| US-20090215965-A1 | POLYMERISATION USING CHAIN TRANSFER AGENTS | THE UNIVERSITY OF LEEDS (GB) | 2009-08-27 | — | — | US | disclosed |
| US-20090215965-A1 | POLYMERISATION USING CHAIN TRANSFER AGENTS | THE UNIVERSITY OF LEEDS (GB) | 2009-08-27 | — | — | US | disclosed |
| US-20090215965-A1 | POLYMERISATION USING CHAIN TRANSFER AGENTS | THE UNIVERSITY OF LEEDS (GB) | 2009-08-27 | — | — | US | disclosed |
| US-20070299221-A1 | Polymerisation Using Chain Transfer Agents | UNIVERSITY OF LEEDS, THE (GB) | 2007-12-27 | — | — | US | disclosed |
| US-20070299221-A1 | Polymerisation Using Chain Transfer Agents | UNIVERSITY OF LEEDS, THE (GB) | 2007-12-27 | — | — | US | disclosed |
| US-20070299221-A1 | Polymerisation Using Chain Transfer Agents | UNIVERSITY OF LEEDS, THE (GB) | 2007-12-27 | — | — | US | disclosed |
| EP-1697424-A1 | POLYMERISATION USING CHAIN TRANSFER AGENTS | THE UNIVERSITY OF LEEDS (GB) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005061555-A1 | POLYMERISATION USING CHAIN TRANSFER AGENTS | THE UNIVERSITY OF LEEDS (GB) | 2005-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160574-A1 | Polymerisation Using Chain Transfer Agents | TRRAP, TRMT1, IPO11 | KMT2A 1898/4885SMN1; SMN2 4353/4885NPSR1 3257/4885 |
| US-20090215965-A1 | POLYMERISATION USING CHAIN TRANSFER AGENTS | TRRAP, TRMT1, IPO11 | KMT2A 1898/4885SMN1; SMN2 4353/4885NPSR1 3257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.