SCHEMBL64099

SCHEMBL64099

COc1cc(N)ccc1N

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.67
CYP3A4 P08684 3/20 0.67
TSHR P16473 2/20 0.67
TDP1 Q9NUW8 2/20 0.67
HSD17B10 Q99714 1/20 0.67
MAPT P10636 4/20 0.59
GAA P10253 3/20 0.59
HTT P42858 2/20 0.59
MAPK1 P28482 1/20 0.59
KDM4E B2RXH2 3/20 0.53
ADRA2B P18089 1/20 0.52
PTGS1 P23219 1/20 0.52
APP P05067 2/20 0.52
NR4A1 P22736 1/20 0.52
USP2 O75604 1/20 0.50
LMNA P02545 1/20 0.48
POLB P06746 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
CHEK1 O14757 2/20 0.45
IDO1 P14902 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29375147 1.00 ALDH1A1 (0.67) ALDH1A1CYP3A4TSHRTDP1HSD17B10
Hydrochloric Acid SCHEMBL10782973 0.98 ALDH1A1 (0.65) ALDH1A1CYP3A4TSHRTDP1HSD17B10
Hydrochloric Acid SCHEMBL10782376 0.98 ALDH1A1 (0.65) ALDH1A1CYP3A4TSHRTDP1HSD17B10
SCHEMBL9161948 0.89 ALDH1A1 (0.55) ALDH1A1CYP3A4TSHRTDP1HSD17B10
SCHEMBL9548255 0.88 CASP1 (0.65) ALDH1A1CYP3A4TSHRTDP1HSD17B10
Methanesulfonamide SCHEMBL9482492 0.88 ALDH1A1 (0.53) ALDH1A1CYP3A4TSHRTDP1HSD17B10
Sulfuric Acid SCHEMBL29558859 0.88 ALDH1A1 (0.53) ALDH1A1CYP3A4TSHRTDP1HSD17B10
Sulfuric Acid SCHEMBL3340873 0.88 ALDH1A1 (0.53) ALDH1A1CYP3A4TSHRTDP1HSD17B10
Sulfuric Acid SCHEMBL8765503 0.86 ALDH1A1 (0.52) ALDH1A1CYP3A4TSHRTDP1HSD17B10
SCHEMBL29466928 0.84 ALDH1A1 (0.66) ALDH1A1CYP3A4TSHRTDP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3491 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12383482-B2 Hair coloring compositions WELLA GERMANY GMBH (DE) 2025-08-12 US claimed
US-20240423887-A1 COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT KAO CORPORATION (JP) 2024-12-26 US claimed
EP-4251285-B1 HAIR COLORING COMPOSITIONS WELLA INT OPERATIONS SWITZERLAND SARL (CH) 2024-09-04 EP claimed
EP-4408376-A1 COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT Kao Corporation (JP) 2024-08-07 EP claimed
CN-118043022-A Composition comprising a dye and an inorganic alkalizing agent 花王株式会社 2024-05-14 CN claimed
US-20240024218-A1 HAIR COLORING COMPOSITIONS WELLA GERMANY GMBH (DE) 2024-01-25 US claimed
CN-117396185-A Hair dyeing composition 威娜国际运营瑞士责任有限公司 2024-01-12 CN claimed
CN-114805805-B Polyimide with high adhesive strength and preparation method and application thereof 深圳先进电子材料国际创新研究院 2023-12-19 CN claimed
CN-115677648-B Synthesis method of high optical purity lactide 扬州大学 2023-12-08 CN claimed
CN-114011462-B Polyaniline loaded zinc catalyst and preparation method and application thereof 扬州大学 2023-10-27 CN claimed
US-4552565-A Hair dyes: diresorcyl sulphide, sulphoxide or sulphone coupling agents HENKEL KGAA (DE) 1985-11-12 US claimed
US-4543425-A 1,3-Diamino-4-(2',2',2',-trifluoroethoxy)-benzene, method of producing the same, and hair coloring composition containing the same WELLA AG (DE) 1985-09-24 US claimed
US-4473375-A COUPLER AND DEVELOPER FOR OXIDATION COLOR DYES WELLA AKTIENGESELLSCHAFT (DE) 1984-09-25 US claimed
EP-0043436-B1 COMPOSITION AND PROCESS FOR DYEING HAIR Wella Aktiengesellschaft (DE) 1983-08-31 EP claimed
EP-0074243-A1 Hair dye composition UNILEVER PLC (GB) 1983-03-16 EP claimed
EP-0043436-A1 Composition and process for dyeing hair Wella Aktiengesellschaft (DE) 1982-01-13 EP claimed
US-4200432-A HAIR DYES L'OREAL (FR) 1980-04-29 US claimed
US-4129414-A Oxidation hair colorants containing water-soluble polyhalogen 3-aminophenols as couplers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1978-12-12 US claimed
US-3961879-A P-PHENYLENEDIAMINE, HAIR L'OREAL (FR) 1976-06-08 US claimed
US-3948596-A Oxidation dye for keratinic fibers containing 2-halo-5-acetaminophenol as a coupler SOCIETE ANONYME DITE: L'OREAL (FR) 1976-04-06 US claimed