Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.54 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HTR5A | P47898 | 1/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1345547 | 0.92 | HDAC1 (0.58) | HDAC1OPRM1OPRD1OPRK1ADAMTS4 | |
| Trifluoroacetic Acid SCHEMBL3345691 | 0.89 | HDAC1 (0.52) | HDAC1DPP4DPP8DPP9DPP7 | |
| Trifluoroacetic Acid SCHEMBL3337486 | 0.87 | AKR1C3 (0.43) | HDAC1DPP4DPP8DPP9DPP7 | |
| Trifluoroacetic Acid SCHEMBL16194886 | 0.85 | DPP4 (0.44) | HDAC1DPP4DPP8DPP9DPP7 | |
| Trifluoroacetic Acid SCHEMBL3341972 | 0.85 | HTR5A (0.58) | HDAC1OPRM1OPRD1OPRK1HTR5A | |
| Trifluoroacetic Acid SCHEMBL3337473 | 0.82 | HDAC1 (0.44) | HDAC1DPP4DPP8DPP9DPP7 | |
| SCHEMBL12607892 | 0.81 | HDAC1 (0.55) | HDAC1OPRM1OPRD1OPRK1NPC1 | |
| Trifluoroacetic Acid SCHEMBL3340260 | 0.81 | SRC (0.50) | HDAC1DPP4OPRM1OPRD1OPRK1 | |
| Trifluoroacetic Acid SCHEMBL3343134 | 0.81 | HTR5A (0.47) | DPP4DPP8DPP9DPP7OPRM1 | |
| SCHEMBL13633142 | 0.80 | OPRM1 (0.45) | HDAC1DPP4OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113512-A1 | METHOD OF TREATMENT USING NOVEL ANTAGONISTS OR INVERSE AGONISTS AT OPIOID RECEPTORS | IGNAR DIANE MICHELE | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113512-A1 | METHOD OF TREATMENT USING NOVEL ANTAGONISTS OR INVERSE AGONISTS AT OPIOID RECEPTORS | OPRL1, OPRD1, OPRK1 | HDAC1 1478/4885DPP4 1431/4885DPP8 2313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.