Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2003037 | 0.89 | TSHR (0.55) | L3MBTL1MAPK1NPC1TP53TSHR | |
| SCHEMBL18785880 | 0.82 | ADRB2 (0.46) | ADRB2ADRB1ADRB3L3MBTL1MAPK1 | |
| SCHEMBL8567872 | 0.82 | ALDH1A1 (0.59) | L3MBTL1MAPK1NPC1TP53TSHR | |
| SCHEMBL3342492 | 0.82 | TDP1 (0.61) | ADRB2ADRB1ADRB3L3MBTL1NPC1 | |
| SCHEMBL28150206 | 0.81 | TSHR (0.52) | ADRB2ADRB1ADRB3L3MBTL1NPC1 | |
| SCHEMBL9247962 | 0.81 | ADRB2 (0.49) | ADRB2ADRB1ADRB3L3MBTL1NPC1 | |
| SCHEMBL13609326 | 0.80 | ADRB2 (0.52) | ADRB2ADRB1ADRB3L3MBTL1MAPK1 | |
| SCHEMBL9242958 | 0.80 | KMT2A (0.54) | L3MBTL1MAPK1NPC1CES2CES1 | |
| SCHEMBL20475052 | 0.79 | CES2 (0.54) | ADRB2ADRB1ADRB3L3MBTL1MAPK1 | |
| SCHEMBL9246081 | 0.79 | RAB9A (0.52) | L3MBTL1NPC1CES2CES1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355774-B1 | Nucleus-fluorinated aromatic carboxylates and processes for their production | ASAHI GLASS CO LTD (JP) | 1995-04-26 | — | — | EP | disclosed |
| US-4985588-A | Nucleus-fluorinated aromatic carboxylates and processes for their production | ASAHI GLASS COMPANY LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0355774-A2 | Nucleus-fluorinated aromatic carboxylates and processes for their production | ASAHI GLASS COMPANY LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |