Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3343884 | 0.92 | DAPK3 (0.50) | RAB9ANPC1EPHX1DAPK3ROCK2 | |
| SCHEMBL3959318 | 0.84 | EPHX1 (0.45) | RAB9ANPC1EPHX1DAPK3ROCK2 | |
| SCHEMBL1241688 | 0.81 | ALDH1A1 (0.52) | RAB9ANPC1EPHX1DAPK3ROCK2 | |
| SCHEMBL13945071 | 0.81 | ALDH1A1 (0.52) | RAB9ANPC1EPHX1DAPK3ROCK2 | |
| SCHEMBL24732190 | 0.78 | MAPT (0.48) | RAB9ANPC1SMN1; SMN2MAPTPOLB | |
| SCHEMBL11470974 | 0.78 | RCE1 (0.47) | RAB9ANPC1EPHX1DAPK3ROCK2 | |
| SCHEMBL14425907 | 0.77 | TDP1 (0.56) | RAB9ADAPK3ROCK2CHEK2PIM1 | |
| SCHEMBL26326822 | 0.76 | RAB9A (0.45) | RAB9ANPC1EPHX1SMN1; SMN2MAPT | |
| SCHEMBL28649814 | 0.76 | SMN1; SMN2 (0.61) | RAB9ANPC1EPHX1SMN1; SMN2MAPT | |
| SCHEMBL28649812 | 0.76 | SMN1; SMN2 (0.61) | RAB9ANPC1EPHX1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233848-B1 | BENZENESULFONAMIDE DERIVATIVES AS INVERSE AGONISTS OF RETINOID-RELATED ORPHAN RECEPTOR GAMMA (ROR GAMMA (T)) | GALDERMA RES & DEV (FR) | 2019-01-30 | — | — | EP | disclosed |