Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | APAF1 | O14727 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27634513 | 0.86 | ACHE (0.40) | ACHENAMPTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL6971478 | 0.85 | ACHE (0.39) | ACHENAMPTHTTL3MBTL1ALDH1A1 | |
| SCHEMBL17454362 | 0.85 | NAMPT (0.37) | ACHENAMPTSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL6156337 | 0.82 | ALDH1A1 (0.43) | ACHENAMPTSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL334433 | 0.80 | NAMPT (0.54) | NAMPTSMN1; SMN2HTTL3MBTL1ALDH1A1 | |
| SCHEMBL23399531 | 0.74 | ACHE (0.40) | ACHESMN1; SMN2HTTL3MBTL1USP2 | |
| SCHEMBL1639886 | 0.74 | GAA (0.51) | NAMPTSMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL19121717 | 0.74 | ACHE (0.35) | ACHESMN1; SMN2HTTPOLBCYP2C19 | |
| SCHEMBL22649179 | 0.73 | SMN1; SMN2 (0.41) | ACHESMN1; SMN2HTTALDH1A1POLB | |
| SCHEMBL26499767 | 0.73 | L3MBTL1 (0.44) | ACHESMN1; SMN2HTTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1580189-A1 | 4-AMINO-5-METHYLPYRAZOLE DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF | Sankyo Agro Company, Limited (JP) | 2005-09-28 | — | — | EP | disclosed |