Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.36 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3348093 | 0.91 | PLA2G2A (0.45) | PLA2G2ATSHRPLA2G1BPLA2G10PLA2G5 | |
| SCHEMBL3346109 | 0.88 | ALDH1A1 (0.44) | HPGDALDH1A1KDM4EHSD17B10PLA2G2A | |
| SCHEMBL3349098 | 0.86 | ALDH1A1 (0.44) | HPGDALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL3345105 | 0.85 | ALDH1A1 (0.45) | HPGDALDH1A1KDM4EHSD17B10PLA2G2A | |
| SCHEMBL3345142 | 0.84 | ALDH1A1 (0.45) | HPGDALDH1A1KDM4EHSD17B10PLA2G2A | |
| SCHEMBL3344740 | 0.83 | ALDH1A1 (0.39) | HPGDALDH1A1KDM4EHSD17B10PLA2G2A | |
| SCHEMBL3345108 | 0.82 | ALDH1A1 (0.43) | HPGDALDH1A1KDM4EHSD17B10PLA2G2A | |
| SCHEMBL3346098 | 0.81 | ALDH1A1 (0.43) | HPGDALDH1A1KDM4EHSD17B10PLA2G2A | |
| SCHEMBL3344022 | 0.80 | PLA2G1B (0.49) | HPGDALDH1A1KDM4EHSD17B10PLA2G2A | |
| SCHEMBL3345066 | 0.80 | TDP1 (0.43) | HPGDALDH1A1KDM4EHSD17B10PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |