Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346049 | 0.90 | PLA2G2A (0.41) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL3346109 | 0.87 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL3344798 | 0.84 | HPGD (0.43) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL3344740 | 0.83 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL3345055 | 0.83 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL3345108 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL3346227 | 0.82 | AKR1B1 (0.39) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL3345105 | 0.82 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL3349098 | 0.81 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL3344022 | 0.81 | PLA2G1B (0.49) | ALDH1A1KDM4EHPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |