Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345023 | 0.91 | PLA2G1B (0.44) | ALDH1A1KDM4EHPGDHSD17B10IDH1 | |
| SCHEMBL3345105 | 0.87 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDHSD17B10PLA2G1B | |
| SCHEMBL3346540 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10IDH1 | |
| SCHEMBL3344798 | 0.81 | HPGD (0.43) | ALDH1A1KDM4EHPGDHSD17B10PLA2G1B | |
| SCHEMBL3349098 | 0.80 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL3345142 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDHSD17B10PLA2G2A | |
| SCHEMBL3346109 | 0.79 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10PLA2G2A | |
| SCHEMBL3346252 | 0.77 | PLA2G2A (0.44) | ALDH1A1KDM4EHPGDHSD17B10PLA2G1B | |
| SCHEMBL3344022 | 0.76 | PLA2G1B (0.49) | ALDH1A1KDM4EHPGDHSD17B10PLA2G1B | |
| SCHEMBL3345055 | 0.76 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDHSD17B10PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |