Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | KDM4B | O94953 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL939897 | 0.73 | DAO (0.41) | LTA4HHPGDSKDM4BKDM5CKDM5B | |
| SCHEMBL31734572 | 0.69 | DYRK1A (0.50) | LTA4HHPGDSDYRK1A | |
| SCHEMBL938207 | 0.68 | GLRA3 (0.52) | LTA4HKDM5CCFTRMAPT | |
| SCHEMBL27735339 | 0.68 | CYP2E1 (0.42) | LTA4HADORA2AADORA1HPGDSBACE1 | |
| SCHEMBL100765 | 0.67 | HPGDS (0.46) | LTA4HADORA2AADORA1HPGDSCFTR | |
| SCHEMBL3709890 | 0.66 | MAPK8 (0.35) | LTA4HADORA2AADORA1HPGDS | |
| SCHEMBL22698306 | 0.65 | LTA4H (0.40) | LTA4HHPGDSDYRK1AMAPT | |
| SCHEMBL4897 | 0.65 | ALDH1A1 (0.49) | LTA4HHPGDSMAPTHSD17B10 | |
| SCHEMBL3246718 | 0.64 | CDC7 (0.47) | DYRK1AMAPTHSD17B10 | |
| SCHEMBL224239 | 0.64 | LTA4H (0.55) | LTA4HHPGDSMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045008-A1 | AMIDES OF THIENO[2,3-d]PYRIMIDINE AND THEIR USE AS ADENOSINE A2a RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2010-04-22 | — | — | WO | disclosed |