Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15435830 | 0.79 | LMNA (0.44) | ACHEALDH1A1 | |
| SCHEMBL12526938 | 0.70 | KDM1A (0.58) | KMT2AACHEALDH1A1 | |
| SCHEMBL17189058 | 0.70 | TSHR (0.50) | KMT2AACHEMEN1 | |
| SCHEMBL7838949 | 0.69 | KMT2A (0.74) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL7436967 | 0.69 | ITGB3 (0.59) | KMT2ANPC1PKMRAB9AACHE | |
| SCHEMBL8928239 | 0.68 | KMT2A (0.65) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL10841965 | 0.67 | ACHE (0.52) | KMT2AACHEALDH1A1 | |
| SCHEMBL10842678 | 0.67 | ACHE (0.52) | KMT2AACHEALDH1A1 | |
| SCHEMBL10842372 | 0.67 | ACHE (0.52) | KMT2AACHEALDH1A1 | |
| SCHEMBL23050851 | 0.65 | MTNR1A (1.00) | MTNR1AMTNR1BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010044054-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-22 | — | — | WO | claimed |
| WO-2010044054-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-22 | — | — | WO | disclosed |