Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2232709 | 0.89 | NOS3 (0.35) | NOS3NOS1NOS2 | |
| SCHEMBL23398355 | 0.85 | FAAH (0.31) | — | |
| SCHEMBL2593550 | 0.85 | FAAH (0.31) | — | |
| SCHEMBL18209644 | 0.83 | HDAC3 (0.30) | — | |
| SCHEMBL17618932 | 0.82 | — | — | |
| SCHEMBL16558626 | 0.78 | CYP1A2 (0.44) | TDP1 | |
| SCHEMBL14246982 | 0.74 | CYP1A2 (0.31) | TDP1 | |
| SCHEMBL3343888 | 0.73 | — | — | |
| SCHEMBL35853 | 0.72 | NOS3 (0.46) | TDP1NOS3NOS1NOS2 | |
| SCHEMBL1697584 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210161825-A1 | CHLOROQUINE-BASED MATERIALS FOR THE TREATMENT OF DISEASES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-06-03 | — | — | US | disclosed |
| US-20100160574-A1 | Polymerisation Using Chain Transfer Agents | THE UNIVERSITY OF LEEDS (GB) | 2010-06-24 | — | — | US | disclosed |
| US-20090215965-A1 | POLYMERISATION USING CHAIN TRANSFER AGENTS | THE UNIVERSITY OF LEEDS (GB) | 2009-08-27 | — | — | US | disclosed |
| US-20070299221-A1 | Polymerisation Using Chain Transfer Agents | UNIVERSITY OF LEEDS, THE (GB) | 2007-12-27 | — | — | US | disclosed |
| EP-1697424-A1 | POLYMERISATION USING CHAIN TRANSFER AGENTS | THE UNIVERSITY OF LEEDS (GB) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005061555-A1 | POLYMERISATION USING CHAIN TRANSFER AGENTS | THE UNIVERSITY OF LEEDS (GB) | 2005-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160574-A1 | Polymerisation Using Chain Transfer Agents | TRRAP, TRMT1, IPO11 | TDP1 1411/4885NOS3 1858/4885NOS1 1164/4885 |
| US-20210161825-A1 | CHLOROQUINE-BASED MATERIALS FOR THE TREATMENT OF DISEASES | NOD2, MYD88, BECN1 | TDP1 2292/4885NOS3 2455/4885NOS1 2522/4885 |
| US-20090215965-A1 | POLYMERISATION USING CHAIN TRANSFER AGENTS | TRRAP, TRMT1, IPO11 | TDP1 1411/4885NOS3 1858/4885NOS1 1164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.