Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL25186018 | 0.85 | KDM4E (0.30) | — | |
| Triphosphate SCHEMBL3343310 | 0.77 | PNP (0.40) | PNPPOLG | |
| SCHEMBL18486650 | 0.73 | PNP (0.39) | PNPPOLG | |
| SCHEMBL676634 | 0.63 | KDM4E (0.43) | PNP | |
| SCHEMBL18486711 | 0.62 | KDM4E (0.38) | PNPPOLG | |
| SCHEMBL3721701 | 0.60 | KDM4E (0.46) | PNPPOLG | |
| Pyrophosphoric Acid SCHEMBL2411229 | 0.57 | KDM4E (0.34) | PNPPOLG | |
| SCHEMBL459237 | 0.51 | TSHR (0.40) | — | |
| Triphosphate SCHEMBL28408391 | 0.51 | FDPS (0.45) | PNPPOLG | |
| (Pyridin-4-Yl)-Methyl-Diphosphate SCHEMBL1652034 | 0.50 | TSHR (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2201107-B1 | NOVEL GTP CYCLOHYDROLASE TYPE IB | UNIV WESTERN HEALTH SCIENCES (US) | 2019-01-16 | — | — | EP | disclosed |
| US-20130218546-A1 | NOVEL GTP CYCLOHYDROLASE TYPE IB | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2013-08-22 | — | — | US | disclosed |
| US-8328934-B2 | Crystal of GTP Cyclohydrolase Type IB | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2012-12-11 | — | — | US | disclosed |
| US-20100291608-A1 | NOVEL GTP CYCLOHYDROLASE TYPE IB | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2010-11-18 | — | — | US | disclosed |
| EP-2201107-A2 | NOVEL GTP CYCLOHYDROLASE TYPE IB | Western University Of Health Sciences (US) | 2010-06-30 | — | — | EP | disclosed |
| WO-2010039115-A9 | NOVEL GTP CYCLOHYDROLASE TYPE IB | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2010-05-27 | — | — | WO | disclosed |
| WO-2010039115-A2 | NOVEL GTP CYCLOHYDROLASE TYPE IB | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2010-04-08 | — | — | WO | disclosed |