Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3778704 | 0.91 | LMNA (0.38) | P2RX3ALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL3772138 | 0.83 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1MAPTNPSR1KDM4E | |
| SCHEMBL3351461 | 0.82 | ALDH1A1 (0.37) | P2RX3ALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL2576023 | 0.81 | HPGD (0.35) | ALDH1A1MAPTNPSR1KDM4EKMT2A | |
| SCHEMBL3772935 | 0.81 | TSHR (0.41) | ALDH1A1L3MBTL1KDM4EHPGDHSD17B10 | |
| SCHEMBL2570555 | 0.80 | ALDH1A1 (0.35) | P2RX3ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3777793 | 0.80 | HPGD (0.39) | P2RX3ALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL3345008 | 0.79 | P2RX3 (0.43) | P2RX3ALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL3770752 | 0.77 | OPRK1 (0.35) | P2RX3MAPTNPSR1LMNANPC1 | |
| SCHEMBL3779299 | 0.77 | DAO (0.40) | ALDH1A1MAPTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |