Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345372 | 0.90 | TDP1 (0.44) | P2RX3TSHRTDP1MAPTTRPC5 | |
| SCHEMBL3344721 | 0.82 | P2RX3 (0.42) | P2RX3ALDH1A1L3MBTL1GAAADORA2A | |
| SCHEMBL3351438 | 0.81 | TSHR (0.41) | TSHRALDH1A1L3MBTL1GAAKDM4E | |
| SCHEMBL3345051 | 0.81 | P2RX3 (0.42) | P2RX3TSHRTDP1MAPTTRPC5 | |
| SCHEMBL13423755 | 0.80 | PTGDR2 (0.44) | TSHRTDP1RORC | |
| SCHEMBL3345503 | 0.79 | P2RX3 (0.42) | P2RX3POLBALDH1A1L3MBTL1TDP1 | |
| SCHEMBL3351455 | 0.77 | PTGDR2 (0.43) | RORC | |
| SCHEMBL3345546 | 0.75 | PTGDR2 (0.50) | RORC | |
| SCHEMBL3345407 | 0.75 | PLA2G2A (0.45) | ALDH1A1KDM4EHPGD | |
| SCHEMBL3344740 | 0.73 | ALDH1A1 (0.39) | P2RX3TSHRALDH1A1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |