Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFB | P00751 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 5/20 | 0.37 |
| ▸ | DRD3 | P35462 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3348766 | 0.77 | PDE4B (0.39) | PDE4B | |
| SCHEMBL3345349 | 0.77 | QDPR (0.45) | PDE4BDRD2 | |
| SCHEMBL3345716 | 0.76 | PDE4B (0.45) | PDE4BDRD2DRD3 | |
| SCHEMBL3312815 | 0.76 | SMN1; SMN2 (0.48) | GAAPDE4BMAPTCRHBPCRHR2 | |
| SCHEMBL12125064 | 0.73 | MAPK1 (0.53) | CFBDRD2DRD3MAPTCRHBP | |
| SCHEMBL2503891 | 0.72 | PDE4B (0.49) | PDE4BMAPTCRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL28795393 | 0.71 | ALDH1A1 (0.39) | MAPTCRHBPCRHR2SMN1; SMN2MAPK1 | |
| SCHEMBL6599141 | 0.71 | HRH3 (0.43) | GAAMAPT | |
| SCHEMBL27715450 | 0.69 | ALDH1A1 (0.48) | PDE4B | |
| SCHEMBL18394286 | 0.68 | PDE4B (0.37) | PDE4BDRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010049731-A1 | PYRAZOLO- AND IMIDAZOPYRIDINYLPYRIMIDINEAMINES AS IGF-1R TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2010-05-06 | — | — | WO | disclosed |