Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3351444 | 0.87 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL3346098 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10HPGDPLA2G1B | |
| SCHEMBL3346093 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL3349142 | 0.80 | ALDH1A1 (0.53) | ALDH1A1KDM4EPDE10AIDH1TSHR | |
| SCHEMBL3347965 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL3348773 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL3351515 | 0.74 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD17B10HPGDPDE10A | |
| SCHEMBL3345090 | 0.73 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL3345079 | 0.72 | ALDH1A1 (0.42) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| SCHEMBL3345023 | 0.72 | PLA2G1B (0.44) | ALDH1A1KDM4EHSD17B10HPGDPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |