Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RORA | P35398 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | RORB | Q92753 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347504 | 0.76 | TDP1 (0.39) | MEN1KMT2AALDH1A1 | |
| SCHEMBL3349136 | 0.72 | CA2 (0.36) | KMT2AALDH1A1 | |
| SCHEMBL1894771 | 0.69 | KMT2A (0.36) | MEN1KMT2AALDH1A1RORARORC | |
| SCHEMBL11779931 | 0.69 | CES2 (0.34) | MEN1KMT2AALDH1A1 | |
| SCHEMBL2480964 | 0.69 | RAB9A (0.41) | MEN1KMT2AALDH1A1 | |
| SCHEMBL3686067 | 0.68 | CA1 (0.42) | KMT2AALDH1A1 | |
| SCHEMBL3347813 | 0.64 | CA2 (0.39) | ALDH1A1 | |
| SCHEMBL18135035 | 0.63 | ERN1 (0.38) | KMT2AALDH1A1 | |
| SCHEMBL3347595 | 0.63 | MMP2 (0.35) | KMT2AALDH1A1 | |
| SCHEMBL2902966 | 0.62 | LMNA (0.33) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010066357-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-17 | — | — | WO | disclosed |