Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 10/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347271 | 0.86 | DYRK1A (0.42) | DYRK1AGRM5TGFBR1SCN5A | |
| SCHEMBL3346913 | 0.86 | DYRK1A (0.42) | DYRK1AGRM5TGFBR1SCN5A | |
| SCHEMBL3347239 | 0.86 | DYRK1A (0.45) | DYRK1AGRM5TGFBR1SCN5A | |
| SCHEMBL3346211 | 0.81 | DYRK1A (0.41) | DYRK1AGRM5TGFBR1SCN5A | |
| SCHEMBL3346476 | 0.79 | DYRK1A (0.41) | DYRK1AGRM5TGFBR1SCN5AL3MBTL1 | |
| SCHEMBL3347011 | 0.79 | DYRK1A (0.41) | DYRK1AGRM5KCNH2TGFBR1SCN5A | |
| SCHEMBL3348434 | 0.78 | GRM5 (0.54) | DYRK1AGRM5KCNH2 | |
| SCHEMBL3346431 | 0.77 | PTPRC (0.36) | GRM5 | |
| SCHEMBL3347287 | 0.77 | DYRK1A (0.44) | DYRK1AGRM5TGFBR1SCN5AMEN1 | |
| SCHEMBL3351713 | 0.77 | KCNN3 (0.38) | GRM5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |